PURPOSE To analyze the indications and outcomes of phototherapeutic keratectomy (PTK) in the developing world. METHODS In this retrospective study, the records of 203 consecutive eyes of 191 patients who had undergone PTK at a tertiary eye care center were evaluated. The parameters assessed were indications of PTK, demographic features, best spectacle-corrected visual acuity (BSCVA), and pach...

PURPOSE To investigate the effects of topical application of the combination of substance P (SP) and insulin-like growth factor (IGF)-1 on corneal epithelial barrier function and epithelial wound closure in rats with capsaicin-induced neurotrophic keratopathy. METHODS Neonatal rats were injected subcutaneously with a single dose of capsaicin to induce neurotrophic keratopathy. Corneal epithel...

Purpose: A chief morbidity of Graves’ eye disease (GED) is upper lid retraction that results in exposure keratopathy and cosmetic deformity. This study was conducted to assess the efficacy of graded anterior blepharotomy to treat upper lid retraction. Methods: Fifty eyelids of 32 patients with GED-associated upper lid retraction causing symptomatic ocular exposure were treated with graded, tran...

PURPOSE To perform ultraviolet (UV) macrophotography of the normal in vivo human cornea, establishing biometric data of the major component of UV absorption for comparison with the Hudson-Stähli (HS) line, the distribution of iron demonstrated by Perl stain, and cases of typical amiodarone keratopathy. METHODS Nonrandomized comparative case series of UV photographs of 76 normal corneas (group...

Bullous Keratopathy, a severe edema of the corneal stroma and epithelium with a characteristic bulla formation on the corneal surface, is a rare opthalmological emergency in cats. Rapidly progressive and uncontrollable by medical means, this condition will result in corneal perforation hours after initial presentation if left unattended. Its pathophysiology and treatment options are reviewed in...

PURPOSE To investigate in vivo morphology of corneal filaments. MATERIALS AND METHODS Over a 12-year period, 19 patients with corneal filaments (7 with keratoconjunctivitis sicca and 12 with other surface diseases) were examined with the slit lamp and photographed by non-contact photomicrography. RESULTS The filaments appeared as variously long and thick threads, attached at one or both end...

BACKGROUND Bullous keratopathy (BK), a severe sight-threatening disorder can have a variety of etiologies such as prophylactic laser iridotomy, intraocular surgery, trauma, and other ocular disorders. However, there are cases of unknown origins, among which a unique clinical entity namely pseudoexfoliation syndrome (PEX) is having increased importance. CASE PRESENTATION In this case note, we ...

To evaluate indications and outcomes of pediatric keratoplasty in a tertiary eye center, and identify factors that affect visual outcomes.We performed a retrospective review of penetrating keratoplasty in children aged 0 to 18 years between 1995 and 2011 in the Asociación para Evitar la Ceguera en México IAP, Hospital "Dr. Luis Sánchez Bulnes".A total of 574 penetrating keratoplasties were perf...

AIMS The aims of this study were to examine the influence of advanced recipient and donor age on the long term outcome of corneal transplantation. METHODS Records of 1036 penetrating corneal grafts in recipients aged > or = 80 years at surgery (defined as the elderly subset) and 8092 donor corneas used for transplantation were obtained from the Australian Corneal Graft Register database, Kapl...