To evaluate the role of thromboxane in hypertension and its complications, we studied mice with targeted disruption of the TXA2 receptor gene in an angiotensin-II-dependent model of hypertension. To determine whether genetic background might alter the physiological actions of the TP receptor, we studied two lines of TP knockout (Tp-/-) mice with distinct genetic backgrounds (C57BL/6 and BALB/c)...

BACKGROUND AND PURPOSE Thymidine Phosphorylase/ Platelet Derived-Endothelial Cell Growth Factor (TP/PD-ECGF) has an angiogenic and chemotherapeutic effects. The aim of this work was to evaluate TP/PD-ECGF expression in gastric adenocarcinoma and find its correlation with established clinicopathological parameters and patients' survival. MATERIALS AND METHODS Samples studied consisted of fifty...

background: antispasmodic and vasorelaxant effects of teucrium polium l . (tp) were mentioned in former studies, so we attempted to evaluate the eventual preventive effect of tp in an acute experimental model of hypertension induced by angiotensin ii (ang ii). methods: forty‑eight male wistar rats were divided randomly into six groups ( n = 8); control group (c), which received only saline, gro...

In this paper1, we present a new approach to construct multicast trees in MPLS networks. This approach utilizes MPLS LSPs between multicast tree branching node routers in order to reduce forwarding states and enhance scalability. In our approach only routers that are acting as multicast tree branching node for a group need to keep forwarding state for that group. All other non-branching node ro...

BACKGROUND We investigated whether thymidine phosphorylase (TP) protein level in renal cell carcinoma (RCC) correlates with clinicopathological characteristics and clinical outcomes. METHODS TP protein level was measured in 116 RCC specimens and in 90 non-neoplastic kidney tissues using a sandwich-type enzyme-linked immunosolvent assay. RESULTS The median TP protein level in RCC tissues was...

Background and Objective: Teucrium polium (TP) has shown hypoglycemic effect in type 1 diabetes induced by single high dose of the cytotoxic agent streptozotocin (STZ) in rats. This study was conducted to evaluate whether its aqueous extract could have such an effect in multiple low-dose STZ-induced model of type 1 diabetes in rats. Materials and Methods: Male Wistar rats were divided into cont...

Objective: Pharmacological effects of carvacrol such as its anti-inflammatory activities have been shows. In this study the effects of carvacrol on serum levels of total protein (TP), phospholipase A2 (PLA2) and histamine in sensitized guinea pigs was evaluated. Materials and Methods: Sensitized guinea pigs were given drinking water alone (group S), drinking water containing three concentration...