The nematodes Caenorhabditis elegans and C. briggsae independently evolved self-fertile hermaphroditism from gonochoristic ancestors. C. briggsae has variably divergent orthologs of nearly all genes in the C. elegans sex determination pathway. Their functional characterization has generally relied on reverse genetic approaches, such as RNA interference and cross-species transgene rescue and mor...

CTnDOT is a 65-kb conjugative transposon present in Bacteroides spp. that confers resistance to erythromycin [erm(F)] and tetracycline [tet(Q)]. An interesting feature of CTnDOT is that both excision from the chromosome and transfer of CTnDOT are stimulated by exposure to tetracycline. However, when no tetracycline is present, transfer of CTnDOT is not detectable. Previous studies suggested tha...

This paper presents PCSMA, an extension to the CSMA/CD protocol (used in the Ethernet) to support both conventional datagram tra c and real-time tra c. The protocol provides predictable packet-delivery bounds for real-time tra c. It does not require changes to existing Ethernet controllers for datagram tra c. Under the new protocol, periodic sources follow a variation of the CSMA protocol that ...

PURPOSE The generally preferred vascular access for neurointerventional procedures is the transfemoral approach (TFA). In complicated cases such as patients with aortic diseases or tortuous vessels, transradial or transbrachial approaches (TRA or TBA) could be good alternatives. The purpose of this study is to review a single medical center experience using the alternative accesses. MATERIALS...

Although sex determination is a universal process in sexually reproducing organisms, sex determination pathways are among the most highly variable genetic systems found in nature. Nevertheless, general principles can be identified among the diversity, like the central role of transformer (tra) in insects. When a functional TRA protein is produced in early embryogenesis, the female sex determini...

Recently the notion of self-similarity has been shown to apply to wide-area and local-area network tra c. In this paper we show evidence that the subset of network tra c that is due to World Wide Web transfers can show characteristics that are consistent with self-similarity, and we present a hypothesized explanation for that self-similarity. Using a set of traces of actual user executions of N...

In Drosophila, the sex of germ cells is determined by cell-autonomous and inductive signals. XY germ cells autonomously enter spermatogenesis when developing in a female host. In contrast, XX germ cells non-autonomously become spermatogenic when developing in a male host. In first instar larvae with two X chromosomes, XX germ cells enter the female or the male pathway depending on the presence ...

INTRODUCTION AND OBJECTIVES several studies have been investigated co-activation can enhance the effectveness of PFM training protocols allowing preventive and therapeutic goals in pelvic floor dysfunctions. The objective of the present study was to investigate if an abdominal-pelvic protocol of training (APT) using gametherapy would allow co-activation of PFM and transversus abdominis/oblique ...

The goal of the study was to assess the efficacy of combined extracellular matrix metalloprotease inducer (EMMPRIN)and death receptor 5 (DR5)-targeted therapy for pancreatic adenocarcinoma in orthotopic mouse models with multimodal imaging. Cytotoxicity of anti-EMMPRIN antibody and anti-DR5 antibody (TRA-8) in MIA PaCa-2 and PANC-1 cell lines was measured by ATPlite assay in vitro. The distribu...

Tra c in ATM networks can be described by numerous parameters. On a per session basis, one may use peak rate, average rate, sustainable rate, average burst duration, average silence duration, and others. In a longer time scale, parameters like the average and peakedness of connection request interarrival times, the average and variance of session holding times, and so on are proposed. Theoretic...