In this issue, Limpitikul et al used the novel CRISPR interference (CRSPRi) strategy to suppress the expression of an arrhythmogenic mutant calmodulin (CaM) gene in human induced pluripotent cell-derived cardiomyocytes (iPSC-CM). This mutant CaM (D130G) is linked with long-QT syndrome (LQTS). The main LQTS mechanism is via a loss in Ca affinity of CaM, resulting in a loss of Ca-dependent inacti...

Background: Apnea can be associated with many complications such as bradycardia, cyanosis, hypotension, hypotonia, hydrocephalus, neurologic complications, and even death. Pharmacological treatment is associated with many side effects. We aimed to investigate the effect of aromatherapy on Apnea in premature newborns. <...

This research examined how environmental attributes near intersections influence the perceived crash risk among school-aged children, which provides information on the potential risks of pedestrian crashes that can guide the development of proactive countermeasures. In a sample of 799 children aged 10-12 years old in Korea, the environmental attributes of intersections perceived as having a hig...

Introduction: Road traffic injuries (RTI) are projected to become the 7th leading cause of mortality worldwide by year 2030. It is that 90% global road injury burden will be borne Low and Middle-Income countries (LMICs), including sub-Saharan Africa. We undertook a systematic literature review assess effectiveness implemented prevention initiatives in Methodology: A English was undertaken per P...

One significant and simultaneously interesting problem in urban mobility has to do with the study of shared spaces where various categories users coexist act together. This paper aims examine behavior preferences pedestrians cyclists, who both a space infrastructure along seafront (which length around 4.0 km) city Thessaloniki, Greece. Furthermore, problems caused by coexistence, such as at loc...

Traffic simulation models play a major role in allowing traffic engineers to assess complex situations such as U-turn section. Such help proposing solutions and alternative scenarios without committing too many expensive resources this are necessary implement strategies the field. Simulation can significantly improve quality of road network planning design urban areas.&nbsp; According filed obs...