BACKGROUND AND OBJECTIVES Blood transfusion is a lifesaving therapy for patients with hemoglobinopathies. However, the need of frequent transfusion carries the risk of transmitting hepatitis B and C infections which are intermediately prevalent in Syria. Despite screening blood donations with sensitive methods, the risk of transmission is still present when infectious blood is donated within th...

BACKGROUND Little is known about the effect of transfusing fresh frozen plasma on the outcome after hepatectomy for hepatocellular carcinoma. PATIENTS AND METHODS Among 410 patients who underwent curative resection between 1992 and 2005, 180 patients had perioperative transfusion with whole blood or packed red blood cells and fresh frozen plasma (group A), while 46 patients were only transfus...

BACKGROUND The aim of the present study was to assess the efficacy of vincristine-laden platelet transfusion for patients with refractory thrombocytopenia. PATIENTS AND METHODS Twenty evaluable patients who received vincristine-laden platelets for refractory thrombocytopenia were included in this retrospective study. Vincristine (1 mg) was added to the platelets and incubated for one hour pri...

BACKGROUND This retrospective, single centre study was conducted to investigate the efficacy of fibrinogen concentrate (FBNc) in decreasing blood requirements and reaching optimal fibrinogen level, in non-trauma, massively transfused, bleeding patients with coagulopathy. METHODS Over a 3-years period, all patients for whom a massive transfusion protocol was activated and had received ≥ 4 unit...

Data from an immunohematology reference laboratory were compiled retrospectively to determine the occurrence of the formation of alloantibodies to low-incidence antigens associated with the African American population (AA-LIAs) among patients with sickle cell disease (SCD). The AA-LIAs under study were V, VS, Js(a), and Go(a). The records from 137 recurrently transfused patients with SCD were s...

(RECEIVED FOR PUBLICATION NOVEMBER 16, 1950) The following observations are concerned with the survival of erythrocytes from three polycythaemic patients transfused into normal recipients and estimated by the method of differential agglutination. The donors were (1) a man aged 60, known to be suffering from polycythaemia vera for seven years. A typical blood count at one time in July, 1949, gav...

Abstract Background One group and hold sample costs approximately £18 to process whilst it £170 prepare administer 1 unit of cross matched blood. We aimed quantify the amount blood cross-matched for elective oesophagectomy gastrectomy cases compare this number units transfused in peri-operative setting (within 24 hours surgery). Current guidance required all patients be 2 pre-operatively. Metho...

Introduction: Raised serum ferritin levels often indicate iron overload, but they are not specific as the elevated in inflammatory disorders, liver diseases, alcohol excess, or malignancy. If regular transfusions required for patient with thalassemia, this doubles rate of accumulation leading to earlier massive overload and iron-related damage. The aim study aimed find out prevalence high among...