نتایج جستجو برای: transplant malignancy
تعداد نتایج: 105796 فیلتر نتایج به سال:
In the December issue of Liver Transplantation, Durand et al. extensively reviewed the issue of extended criteria donors in liver transplantation. They mentioned the problem of donors with a history of malignancy and recommended in Table 2 that donors with grade III/IV central nervous system (CNS) malignant tumors be rejected as the risk of malignancy transmission is estimated at 40%. This esti...
The proliferation signal inhibitors [PSIs; mammalian target of rapamycin (mTOR) inhibitors] are widely used for immunosuppression in transplant recipients. Alongside their immunosuppressive properties, PSIs also have substantial anti-neoplastic activity, as a result of their inhibition of cellular signalling pathways involved in critical functions such as cell division, T-cell activation, invas...
INTRODUCTION The long-term use of immunosuppressive agents for prevention of allograft rejection increases the risk of malignancy approximately 100 times as high as that in the general population and Kaposi's sarcoma (KS) is a relatively common malignancy after kidney transplantation. The aim of present study was to investigate the frequency of KS in patients with kidney transplantation in 20 y...
Surgical advances, in conjunction with more effective immunosuppressive strategies, have propelled the field of lung transplantation forward and have made intermediate-term survival an achievable goal. Nonetheless, the post-transplant course is often marked by complications that threaten both the quality and duration of the recipient's life. Many of the medical complications that arise are the ...
BK virus infection is a challenging complication in renal allograft recipients and has been associated with hematuria, ureteral stenosis, nephropathy and malignancy. BK virus infection occurs early during childhood and the virus lays dormant in uroepithelial cells. Reactivation of the virus in renal transplant recipients is particularly worrisome because of its propensity to cause local damage ...
Introduction: Malignancy management in renal transplant recipients is becoming a major factor affecting long term patient survival. Thus, we intended to evaluate both incidence and prognosis of malignant diseases following renal transplantation at a single centre in Portugal. Methods: We studied retrospectively the 2,358 patients who underwent kidney transplantation (KT) between 1983 and 2014...
Abstract Background and Aims HLA compatibility is a key issue in deceased living kidney allocation, although the continuous improvement of immunosuppressive protocols might have reduced its relevance. However, an increased immunosuppression associated with several adverse events, including development post-transplant neoplasia. Indeed, reports demonstrated that drug efficiency corresponded to i...
background : guillain-barre syndrome is an unusual complication of hematopoietic stem cell transplantation but it is extremely rare after solid organ transplantation such as kidney or liver transplantation case report : a 48-year-old man, a case of kidney transplantation presented with generalized weakness in an ascending pattern. history and examination were compatible with the diagnosis of gu...
Twenty patients who were positive for hepatitis B surface antigen (HBsAg) underwent allogeneic marrow transplant for malignancy or other underlying hematologic disease between 1975 and 1986. After transplant, one patient had serologic evidence of hepatitis B virus (HBV) reactivation whereas three patients had evidence of an immune response to HBV. Among four patients with serologic follow-up of...
The 2009 Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline on the monitoring, management, and treatment of kidney transplant recipients is intended to assist the practitioner caring for adults and children after kidney transplantation. The guideline development process followed an evidence-based approach, and management recommendations are based on systematic reviews...
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