Evolution Strategies (ES) have recently been demonstrated to be a viable alternative to reinforcement learning (RL) algorithms on a set of challenging deep RL problems, including Atari games and MuJoCo humanoid locomotion benchmarks. While the ES algorithms in that work belonged to the specialized class of natural evolution strategies (which resemble approximate gradient RL algorithms, such as ...

The authors describe surgical treatment for high risk patients with abdominal aortic aneurysms of complicated morphology for standard endovascular repair. This was achieved by combining endovascular stent-grafting for aneurysmal sac exclusion with conventional vascular surgical procedures.

Alcoholism is a complex relapsing disorder of heterogeneous etiology, affecting people internationally. Alcohol dependence is a cumulative response of inability to stop drinking, craving and developing the symptoms of physical dependence and tolerance. In past two decades, mounting evidence has suggested that alcoholism or alcohol addiction is a host of major psychological, social, financial an...

The incidence of acute otitis media and its response to treatment only with nose drops and analgesics (but without antibiotics or myringotomy) were assessed over three months by 45 doctors in and around Tilburg. In addition, over 17 months 60 general practitioners assessed the effects of this limited treatment in children aged 2 to 12 years and referred all those in whom the condition took an u...

The management of non-specific low back pain relies chiefly on analgesics, education, and physical exercises. Of the many risk factors for chronicity, the most relevant are psychosocial and occupational. Identifying homogeneous patient subgroups helps to develop personalized treatment strategies, thus improving the outcomes. Current clinical research is focusing on subgroup identification via s...

Dentinogenesis imperfecta (DI) type 2 is a disease inherited in a simple autosomal dominant mode. As soon as the teeth erupt the parents may notice the problem and look for a pediatric dentist's advice and treatment. Early diagnosis and treatment of DI is recommended, as it may prevent or intercept deterioration of the teeth and occlusion and improve esthetics. The purpose of this article is to...