Using a whole-cell antigen antibody to Trichomonas vaginalis was measured by an enzyme-linked immunosorbent assay (ELISA). IgG antibody was found in sera from only three of 99 children under 12 years of age. In contrast, serum IgG or IgM antibody or both were detected in 80.4% of women who had vaginal trichomoniasis and in 13.7% of uninfected women. Although antibody was found in cervical and v...

Trichomoniasis, caused by the parasitic protozoan Trichomonas vaginalis, is the most common non-viral sexually-transmitted disease, and there can be severe complications from trichomoniasis. Antibiotic resistance in T. vaginalis is increasing, but there are currently no alternatives treatment options. There is a need to discover and develop new chemotherapeutic alternatives. Plant-derived natur...

Sexually transmitted infections (STIs) are infections that are mainly transmitted from person-to-person through sexual contact[1]. Almost 30 types of causative bacteria, viruses and parasites have been isolated, which are responsible for multiple sexually transmissible diseases such as gonorrhea, chlamydial infection, syphilis, trichomoniasis, chancroid, genital herpes, human immunodeficiency v...

To determine the minimum effective dose of metronidazole in the treatment of vaginal trichomoniasis, a randomised clinical trial comparing single 1-g and 2-g doses was carried out on 163 patients attending sexually transmitted diseases and family planning clinics. Seventy-two of 86 (84%) patients receiving a single 2-g dose of metronidazole were cured compared with only 42 of 77 (55%) receiving...

  To determine the prevalence of trichomoniasis in Sirjan city, the vaginal discharges of 500 women were examined by direct smear and culture methods from June to December 1992. ( Two hundred thirty women referred to vali-asr polyclinic and 270 to the health center number 3). The mean age of the women was 30 years and a higher percentage of referrals were between 30-34 years. In respect to the...

This study interviewed 2,272 women from a low income community in California, USA who completed a questionnaire entitled Risk Behavior Assessment that captured risky drug and sexual behavior. The logistic regression model included gonorrhea, chlamydia, syphilis, warts, crack, and sex trading for money as well as racial and ethnic differences. It was evident that Trichomonas Vaginalis can co-exi...

The multistep translational science behind new drugs comprehends the entire process through laboratory, clinical, and community observations turned into health interventions. development of drug options from discovering targets leading compounds in basic research for implementing therapeutic guidelines contributes to emergence policies essential infection control. This review updates scenario m...