Background and Aims: Trichomonas vaginalis is a flagellated protozoa that is associated with vaginitis, cervicitis, urethritis and other vaginal disorders. Current study aimed to evaluate the anti-Trichomonas activity of Medicago sativa and Satureja hortensis, in vitro. Materials and Methods: Ethanolic extract of Medicago sativa and Satureja hortensis were obtained by rotary evaporator. anti-T...

BACKGROUND Trichomonas vaginalis is protozoan parasite responsible for trichomoniasis and is more common in high-risk behavior group such as prostitute individuals. Interest in trichomoniasis is due to increase one's susceptibility to viruses such as herpes, human papillomavirus and HIV. The aim of this study was to find genotypic differences between the isolates. METHODS Forty isolates from ...

Background-A recent report demonstrated the immunogenic character of the cysteine proteinases of Trichomonas vaginalis. It was of interest, therefore, to examine for the presence of serum anti-proteinase antibody among patients with trichomoniasis. Methods-An immunoprecipitation assay was used involving protein A-bearing Staphylococcus aureus first coated with the IgG fraction ofgoat anti-human...

BACKGROUND Trichomonas vaginalis infection is a common sexually transmitted protozoal infection and is associated with several adverse health outcomes, such as preterm birth, delivery of a low-birth weight infant, and facilitation of sexual transmission of human immunodeficiency virus. The annual incidence in the United States has been estimated to be 3-5 million cases. However, there are no da...

BACKGROUND Trichomonas vaginalis is a parasitic protozoan which causes most common non viral sexually transmitted disease trichomoniasis. Direct microscopic examination of vaginal fluid remains the most widely used diagnostic test. Although, wet mount examination is the most cost-effective diagnostic test, but it has low sensitivity resulting in under diagnosis of the disease. Therefore, to ove...

Cytologists have recognized Trichomonas vaginalis in stained preparations of cervical and vaginal material for a number of years (Papanicolaou and Traut, 1943). However, clinicians have been slow to accept the cytological diagnosis of T. vaginalis, possibly because the organisms may be reported in women who are asymptomatic, and possibly because they may be seen in fixed smears when motile form...

Wide-spread protozoan parasites carry endosymbiotic dsRNA viruses with uncharted implications to the human host. Among them, Trichomonas vaginalis, a parasite adapted to the human genitourinary tract, infects globally ∼250 million each year rendering them more susceptible to devastating pregnancy complications (especially preterm birth), HIV infection and HPV-related cancer. While first-line an...

trichomonas vaginalis infection is a sexually transmitted infection causing vaginitis and acute inflammatory disease of the genital mucosa. although metronidazole resistance in t. vaginalis is well documented, the only drug approved for the treatment of trichomoniasis in some countries is metronidazole. genus allium plants including garlic; shallot and onion have had an important medicinal role...

Two hundred and fifty six unselected women, 50 of whom had urinary symptoms (frequency of urination or dysuria, or both), and who were attending a department of genitourinary medicine, were investigated. The urinary symptoms were associated both with pyuria and the isolation of undoubted pathogens from midstream urine (MSU) specimens. No associations were found between urinary symptoms and the ...

The multistep translational science behind new drugs comprehends the entire process through laboratory, clinical, and community observations turned into health interventions. development of drug options from discovering targets leading compounds in basic research for implementing therapeutic guidelines contributes to emergence policies essential infection control. This review updates scenario m...