To investigate the relationship between serum lipids and alkaline phosphatase during normal pregnancy, we measured triglyceride, total cholesterol, HDL-cholesterol, and LDL-cholesterol concentrations and alkaline phosphatase activity in serum samples from 546 apparently healthy pregnant, postpartum, and nonpregnant women. Serum HDL-cholesterol levels did not change significantly during pregnanc...

OBJECTIVE To determine whether plasma triglyceride levels in adult Glycosylphosphatidylinositol HDL-binding protein 1 (GPIHBP1)-deficient (Gpihbp1(-/-)) mice would be sensitive to cholesterol intake. METHODS AND RESULTS Gpihbp1(-/-) mice were fed a Western diet containing 0.15% cholesterol. After 4 to 8 weeks, their plasma triglyceride levels were 113 to 135 mmol/L. When 0.005% ezetimibe was ...

Mean serum cholesterol and triglyceride concentrations were higher for two groups of sedentary middle-aged and elderly men than for a group of physically-active, middle-aged farmers, all from rural Puriscal, Costa Rica. The mean serum cholesterol, triglyceride, and high-density lipoprotein (HDL)-risk factor levels of the three groups were all higher than the comparable US means. Dietary fat and...

Ezetimibe potently and selectively inhibits cholesterol absorption in the intestine, thereby reducing plasma cholesterol in preclinical models of hypercholesterolemia. Clinical trials have demonstrated that ezetimibe lowers LDL cholesterol and raises HDL cholesterol in humans. The effect of ezetimibe on other dyslipidemias, particularly hypertriglyceridemia, is not yet known. In the present stu...

Reducing low-density lipoprotein cholesterol (LDL-C) levels does not eliminate cardiovascular risk; most patients obtain only a 25% to 35% risk reduction. When the triglyceride level is above 200 mg/dL, non–high-density lipoprotein cholesterol (non–HDL-C) is a more precise therapeutic target than LDL-C. It can serve as an excellent proxy for assessing the total number of circulating atherogenic...

OBJECTIVE The aim of the study was to investigate the relationships between remnant-like particle (RLP) cholesterol, triglycerides, and insulin resistance in nonobese Japanese type 2 diabetic patients. RESEARCH DESIGN AND METHODS A total of 86 nonobese Japanese type 2 diabetic patients (72 men and 14 women, aged 40-83 years, BMI 20.1-26.6 kg/m2) were studied. BMI, HbA1c levels, and fasting co...

Objective: To study the prevalence of metabolic syndrome in overweight/obese children and its association with nonalcoholic fatty liver disease. Patients and Methods: Thirty-four overweight and obese children, age 2 to 13 years, body mass index (BMI) ^! 85 th percentile, were studied for the prevalence of metabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD). Laboratory analys...

Dyslipidemia, being one of the important independent modifiable risk factors for cardiovascular disease (CVD), is increasing in prevalence among all ethnic groups across globe including tribal population. Because paucity data, we aimed at estimating dyslipidemia and its associated population Kashmir. This cross-sectional survey studied 991 adult (Gujjars Bakarwals) subjects from five randomly s...

consequences that lead to an increase in risk of atherosclerosis patients with epilepsy, several studies have reported the commonly used antiepileptic drugs like phenytoin, and carbamazepine serum total Cholesterol, High Density Lipoproteins Cholesterol (HDL-C) Low lipoprotein ( LDL-C ) levels Triglyceride (TG) .The aim this study assess compare lipid profile young adult treated by anti-epilept...