Desde un enfoque ontogenético, esta es una propuesta reelaborada de la noción Quinian bootstrapping (QB) para su aplicación a teoría metáfora conceptual (TMC), específicamente al vínculo cognitivo entre el pensamiento esquemático del dominio-fuente y correspondiente dominio-destino. Frente escaso desarrollo teórico específico TMC respecto ontogenia intersubjetividad procesamiento metafórico, es...

We report the completely annotated genome sequence of Mycobacterium tuberculosis Erdman (TMC 107; ATCC 35801), which is a well-known laboratory strain of M. tuberculosis.

A concise, total synthesis of the proteasome inhibitors TMC-95A/B has been accomplished. The synthesis features the use of an L-serine-derived E-selective modified Julia olefination reaction to ultimately control the stereochemical outcome of the highly oxidized tryptophan fragment. Additionally, the limited use of protecting groups at a late stage of the total synthesis allowed for its complet...

We describe a new on-line sensitive and selective procedure for the determination of trivalent hexavalent chromium in liquid samples by tailor-made contactor (TMC), specifically membrane annular TMC, coupled with inductively plasma optical detection. The TMC was designed developed to integrate extraction stripping phases analyte one module minimize solvent’s consumption maximize speed transport...

Antiretroviral treatment has modified the course of human immunodeficiency virus (HIV) infection transforming it into a chronic disease. However, as treatment is conceived "for life", more effective and safety drugs, overcoming the growing resistance of the virus are required. New molecules may block the known viral targets or other new ones. The mechanism of the virus union and entrance to the...

BACKGROUND Several reports indicate that drinking water arsenic (WAs) and manganese (WMn) are associated with children's intellectual function. Very little is known, however, about possible associations with other neurologic outcomes such as motor function. METHODS We investigated the associations of WAs and WMn with motor function in 304 children in Bangladesh, 8-11 years of age. We measured...