نتایج جستجو برای: trypanocidal activity

تعداد نتایج: 1134678  

Journal: :Antimicrobial Agents and Chemotherapy 2021

A common strategy to identify new antiparasitic agents is the targeting of proteases, due their essential contributions parasite growth and development. Metacaspases (MCAs) are cysteine proteases present in fungi, protozoa, plants.

Journal: :The Onderstepoort journal of veterinary research 2003
G L Mugunieri G A Murilla

A household survey was conducted in 21 villages of Kwale district, Kenya, to assess farmers' trypanocidal drug use characteristics for treatment of bovine trypanosomosis and their relationship to drug effectiveness. Descriptive statistical tools were used to summarize the farmers' drug use patterns. The chi-square test was the done to establish the relationship between proper drug use and recov...

2016
Guilherme Curty Lechuga Júlio Cesar Borges Claudia Magalhães Calvet Humberto Pinheiro de Araújo Aline Araujo Zuma Samara Braga do Nascimento Maria Cristina Machado Motta Alice Maria Rolim Bernardino Mirian Claudia de Souza Pereira Saulo Cabral Bourguignon

Chagas disease is a neglected tropical disease caused by the flagellated protozoan Trypanosoma cruzi. The current drugs used to treat this disease have limited efficacy and produce severe side effects. Quinolines, nitrogen heterocycle compounds that form complexes with heme, have a broad spectrum of antiprotozoal activity and are a promising class of new compounds for Chagas disease chemotherap...

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