Tuberculosis is one of the most common disease in developing world with its pulmonary and extra pulmonary forms. The treatment of tubercular pleural effusion is full of controversies, especially in the use of glucocorticoid. This case study shows the dramatic improvement with the use of glucocorticoid along with ATT. So, this case supports the aid in use of steroid in Tubercular pleural effusio...

1. The acetone-soluble fat of tubercle bacilli produces a profound cellular reaction when injected into normal animals. The reaction involves every type of connective tissue cell. Hemorrhage, formation of adhesions and of tubercular tissue occur. The extent of the reaction is roughly proportional to the amount of material injected. 2. The reaction induced by the lipoid is much less extensive an...

Introduction Sternal involvement is seen in less than 1% of skeletal tuberculosis. Sternal TB was first reported in 1918 [1] and until 2007, fewer than 35 cases are documented in English literature [2]. Even in tubercular endemic belts, there are only limited and isolated case reports [3]. We report two cases of tubercular abscess of sternum in otherwise healthy individuals. Both cases were dia...

Primary tubercular osteomyelitis of sternum is a rare clinical entity and involvement of manubrio-sternal joint is even rarer, with only few cases reported in the literature. Tuberculous sternal involvement is seen in approximately 1% of all skeletal TB cases. We report an unusual case of primary manubrio-sternal joint tuberculosis presenting as vague anterior chest wall swelling and pain. ESR ...

In the late 19th and early 20th centuries, two medicine circles existed in Indian country: one Native and one Euro-American. Traditional doctors among First Nations peoples approached disease in spiritual ways and also used herbal medicine to treat their patients. First Nations people tried to treat infectious diseases brought by newcomers through plant medicine, ritual, and ceremony. Generally...

A 55yr old gentleman known diabetic and hypertensive presented with breathlessness and tingling sensation of both upper and lower limbs with strong family history of similar neurological problems. On extensive evaluation he was found to have amyloidic peripheral neuropathy with large pericardial effusion. Tubercular etiology was confirmed by pericardial fluid PCR and culture. Here the diagnosti...

Micrococcus luteus was employed for the assay of rifampicin in fixed-dose combinations (FDCs) of anti-tubercular drugs containing rifampicin, isoniazid, pyrazinamide and ethambutal. The microbiological assay was compared with spectrophotometric assay for estimation of rifampicin in the FDCs as well as in dissolution studies of the FDCs. The microbiological method was found to be more sensitive ...

This study evaluated the possibility to use six phages specific to the Mycobacterium tuberculosis lipoarabinomannan (LAM) as tools for tubercular serodiagnosis. We analysed sera samples from 30 subjects with active tuberculosis (TB+), 30 with latent tubercular infection (LTBI) and 60 healthy subjects as controls (K). Our data indicated a good antibody response of the TB+ and LTBI patients again...

The use of Cefoxitin MIC test has not been recommended by the CLSI-AST, but its performance was equivalent to Cefoxitin DD when using modiÞ ed breakpoints of less than or equal to 4 μg/ml for susceptible and greater than orequal to 8 μg/ml for resistance. The results of Cefoxitin DD method were better for isolates with Oxacillin MIC between 4-6 μg/ml (Table). Both Oxacillin DD and Cefoxitin DD ...