purification of drinking and industrial water required usage of high molecular weight polymer to cause flocculation process of dispersed suspension of contaminants. polyelectrolytes, including ionic polyacrylamide are especially appropriate for these purposes, because in this case the suspension stability can be controlled by both steric and electrostatic forces. thus the influence of solution ...

BACKGROUND Most hemodialysis patients present with chronic systemic inflammation characterized by the elevation of serum C-reactive protein (CRP) levels and/or the production of proinflammatory interleukins by the immune system in response to the hemodialysis process. Plasma ferritin(PF) is one of the parameters used to correct anemia. An PF level of >500 ng/mL is not recommended for correction...

The binding of bovine serum albumin (BSA) and β-lactoglobulin (BLG) to TTMA (a cationic gold nanoparticle coupled to 3,6,9,12-tetraoxatricosan-1-aminium, 23-mercapto-N,N,N-trimethyl) was studied by high-resolution turbidimetry (to observe a critical pH for binding), dynamic light scattering (to monitor particle growth), and isothermal titration calorimetry (to measure binding energetics), all a...

Cyclostreptin (FR182877), a bacterial natural product, was reported to have weak paclitaxel-like activity with tubulin but antitumor activity in vivo. We used synthetic cyclostreptin in studies of its mechanism of action. Although less potent than paclitaxel in several human cancer cell lines, cyclostreptin was active against cells resistant to paclitaxel and epothilone A. At equitoxic concentr...

OBJECTIVES IL-35 is a member of the IL-12 family consisting of p35/IL-12a and EBI3/IL-27b subunits. IL-35 exerts immunomodulatory activities in experimental and human autoimmune inflammatory conditions. Our aim was to assess IL-35 expression in the skin and circulation of SSc patients and to characterize its potential association with SSc-related features. METHODS Expression of IL-35 in skin ...

the biopolymer-based nanocomplexes are a group of nanocapsules that are used for encapsulation and control delivery of nutraceuticals. they are formed by binding of proteins and polysaccharides. in this study, complex formation between pectin and sodium caseinate was taken place by addition of pectin solutions(0.2, 0.45 and 0.7 % w/v) into the caseinate solutions (0.5, 1 and 1.5 % w/v) and adju...

The objective of the present work was to formulate a self-emulsifying drug delivery system (SEDDS) for simvastatin, which is widely used in the treatment of hypercholesterolemia and dyslipidemia as an adjunct to diet. Simvastatin SEDDS were formulated using a 1:1 (V/V) mixture of diesters of caprylic/capric acids and polyglycolyzed glycerides with varying concentrations of polyoxy castor oil an...

A series of thermoresponsive diblock copolymers of poly[2-(dimethylamino)ethyl methacrylate-block-di(ethyleneglycol) methyl ether methacrylate], poly(DMAEMA-b-DEGMA), were synthesized by reversible addition−fragmentation chain transfer (RAFT) polymerizations. The series consist of diblock and quasi diblock copolymers. Sequential monomer addition was used for the quasi diblock copolymer synthesi...

BACKGROUND The responses of immunological factors to different subtypes of Kawasaki disease (KD) remain poorly understood. METHODS We recruited 388 patients with KD, 160 patients with infectious febrile disease and 85 normal children who served as control subjects. Both the levels and percentages of T lymphocyte subsets, natural killer cells (NK cells) and B cells were analyzed via flow cytom...