Luc Demortier The Rockefeller University, New York, NY 10021, U.S.A. Abstract The standard Bayesian treatment of systematic uncertainties is to integrate out the corresponding nuisance parameters from the joint posterior density for all parameters. We apply this formalism to measurements in which the data cannot distinguish between nuisance parameters and parameters of interest, and show that i...

Freezing of gait (FoG) is a motor impairment among patients with advanced Parkinson’s disease which is associated with falls and has a negative impact on a patient’s quality of life. Wearable systems have been developed to detect FoG and to help patients resume walking by means of rhythmical cueing. A step further is to predict the FoG and start cueing a few seconds before it happens, which mig...

This paper concerns the reconstruction of the absorption and scattering parameters in a time-dependent linear transport equation from knowledge of angularly averaged measurements performed at the boundary of a domain of interest. Such measurement settings find applications in medical and geophysical imaging. We show that the absorption coefficient and the spatial component of the scattering coe...

The article presents an outline of the requirements concerning the planning of preclinical and clinical studies, necessary for the legal approval of a medicinal product. It describes the clinical research plan of innovative and generic pharmaceutical products, taking into account the specific situations in which the assessment of biological equivalence of a generic product is not possible based...

We argue that in the high energy QCD a true black disk wave function consists not only of many gluons but also from many quarks. This corresponds to necessity of nonvacuum reggeon loops in formation of a black disk. The result comes from decomposition of the black disk S-matrix in characters on group manifold. Usually black disk defined as some dense state, which absorbs any projectile. In this...