More than three decades years ago, Aharon Katchalsky and Ora Kedem (1958, 1962) pointed out that the essence of biological transport is coupling. This insight was not so much a deduction as a concise summary of observations. At an elementary level, movement of a solute in the simplest aqueous solution implies movement of a hydration shell, and therefore movement of water, thence coupling of wat...

BACKGROUND With the 2-way mixed model, one a fixed factor and the other random, the procedure followed to test statistical significance of the random factor has been the focus of a heated controversy in theoretical and applied statistics, and the debating continues even now. One of the main consequences of this controversy is that the position defended in the classical ANOVA texts on the hypoth...

We introduce a novel latent grouping model for predicting the relevance of a new document to a user. The model assumes a latent group structure for both users and documents. We compared the model against a state-of-the-art method, the User Rating Profile model, where only users have a latent group structure. We estimate both models by Gibbs sampling. The new method predicts relevance more accur...

We present an algorithm to estimate the two-way fixed effect linear model. The algorithm relies on the Frisch-Waugh-Lovell theorem and applies to ordinary least squares (OLS), two-stage least squares (TSLS) and generalized method of moments (GMM) estimators. The coefficients of interest are computed using the residuals from the projection of all variables on the two sets of fixed effects. Our a...

We present an algorithm to estimate the two-way fixed effect linear model. The algorithm relies on the Frisch-Waugh-Lovell Theorem and applies to ordinary least squares (OLS), two-stage least squares (TSLS) and generalized method of moments estimators (GMM). The coefficients of interest are computed using the residuals from the projection of all variables on the two sets of fixed-effects. Our a...

Resumen Background: With the 2-way mixed model, one a fi xed factor and the other random, the procedure followed to test statistical signifi cance of the random factor has been the focus of a heated controversy in theoretical and applied statistics, and the debating continues even now. One of the main consequences of this controversy is that the position defended in the classical ANOVA texts on...

We study completely asymmetric two-channel exclusion processes in one dimension. It describes a two-way traffic flow with cars moving in opposite directions. The interchannel interaction makes cars slow down in the vicinity of approaching cars in the other lane. Particularly, we consider in detail the system with a finite density of cars on one lane and a single car on the other. When the inter...

Within the formalism of the matrix product ansatz, we study a two-species asymmetric exclusion process with backward and forward site-ordered sequential updates. This model, which was originally introduced with the random sequential update [J. Phys. A 30, 8497 (1997)], describes a two-way traffic flow with a dynamic impurity and shows a phase transition between the free flow and the traffic jam...

Two-way selection is a common phenomenon in nature and society. It appears in the processes like choosing a mate between men and women, making contracts between job hunters and recruiters, and trading between buyers and sellers. In this paper, we propose a model of two-way selection system, and present its analytical solution for the expectation of successful matching total and the regular patt...