In pig production, the terms "growth promoter", "performance enhancer", and "digestive enhancer" include a diverse range of products ranging from simple chemicals (copper salts) to chemically produced antibacterial compounds (carbadox) to antibiotics (tylosin, avilamycin, salinomycin, virginiamycin). Most of the antibiotic group are produced during a fermentation process by yeasts, moulds, and ...

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While accessing to the European Union the Republic of Finland obtained a derogation enabling it to maintain the ban on its territory of the use of tylosin and spiramycin as feed additives. According to the Treaty of Accession, Finland was due to provide its request for adaptation of Community legislation before 31 December 1997, which should be accompanied by a detailed scientific statement of ...

Essential roles for both the 23-O-mycinosyl and 4''-O-acyl moieties of 4''-O-acyltylosin derivatives in the expression of antimicrobial activity against multiple macrolide-resistant strains of Staphylococci and mycoplasmas were demonstrated by in vitro comparison of the MICs of erythromycin, josamycin, tylosin and its 3- and 4''-O-acyl derivatives, demycinosyltylosin (DMT) and its 3- and 4''-O-...

Minimum lethal concentrations (MLC) and minimum inhibitory concentrations (MIC) were determined in vitro for 8 antibiotics against 9 isolates of Mycoplasma synoviae. Of the antibiotics tested, tylosin had the highest activity, followed closely by chlortetracycline, lincomycin, oxytetracycline, spectinomycin, and tetracycline. Neomycin and erythromycin were less effective. Two antibiotic combina...

Ninety-six enterococcus isolates from fecal samples of pigs receiving tylosin as an antimicrobial growth promoter and 59 isolates obtained in the same farms 5 to 6 months after the ban of antimicrobial growth promoters in Switzerland were tested for susceptibility to nine antimicrobial agents. A clear decrease in resistance to macrolides, lincosamides, and tetracycline was visible after the ban...

Abstract
 Increased activity of aldose reductase (AR) and sorbitol dehydrogenase (SDH) are the major causes diabetic complications. Thus, inhibition these two enzymes is vital in preventing As synthesis new effective AR SDH enzyme inhibitors quite difficult, we have investigated effects antibiotics, which already widely used medicine, on enzymes. were purified from bovine kidney, vitro ant...