Background: Considerable evidence suggests that oxidative stress affects diabetes mellitus (DM) and contributes to its complications. Vitamin D has been shown to possess antioxidant properties. The aim of this study was to determine the association between serum levels of calcifediol (25-OH-D), an indicator of vitamin D status, and lipid profiles with oxidative stress in patients with type 2 di...

Objective: Exercise and nutrition as life style modification strategies for the prevention and control of diabetes are considered. The aim of present study was to assess the effects of saffron consumption and aerobic exercises on serum levels of Heart-type fatty acid binding protein (HFABP) and Troponin T in type2 diabetes (T2DM) patients. Materials and Methods: This study was a quasi-experime...

Abstract Objective: It has been reported that adenosine deaminase (ADA) is a good marker for insulin function but its clinical significance in type 2 diabetes mellitus (T2DM) is not yet characterized. This study aims to assess the association of ADA with glycated hemoglobin (HbA1c) and uric acid (UA) in T2DM patients. Materials and Methods: The study population consisted of 120 subjects divi...

Type 2 Diabetes Mellitus (T2DM) is the leading cause of chronic kidney disease (CKD), accounting for almost half all cases failure that necessitate replacement therapy. Cardiovascular (CVD) death in patients with T2DM and CKD. To lower blood glucose levels by inhibiting reabsorption proximal tubule, sodium/glucose cotransporter inhibitors (SGLT2-i) were developed. Consistent reductions risks se...

BACKGROUND Type 2 diabetes (T2DM) is one of the most prevalent and costly chronic conditions in the United States. Macrovascular disease (MVD) remains a common and costly comorbidity in T2DM. Understanding the impact of MVD on total health care costs in patients with T2DM is of great importance to managed care organizations (MCOs). OBJECTIVE To examine from the perspective of an MCO the impac...

16.15.03-022010 Introduction Following publication of the December 2008 FDA Guidance for Industry Diabetes Mellitus — Evaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat Type 2 Diabetes, assessment of cardiovascular safety has become a critical focus during the development of new antidiabetic therapies for Type 2 diabetes mellitus (T2DM). The importance of this guidance docume...

OBJECTIVE To prospectively assess the relationship between overweight/obesity and incidence of type 2 diabetes mellitus (T2DM) among Mexicans aged 50+, assessing effects of age, genetic predisposition, education, physical activity, and place of residence. MATERIALS AND METHODS The Mexican Health and Aging Study (MHAS) was used to prospectively follow respondents free of diabetes in 2001 who b...

The purpose of the study was to evaluate the serum level of calcium (Ca) and iron (Fe) in type 2 diabetes mellitus (T2DM) with periodontitis subjects. A total of 450 subjects participated in the study, who were all distributed equally into three groups as control healthy individuals (group I), T2DM without periodontitis (group II), and T2DM with periodontitis (group III), matched for age, sex, ...

The liver plays a vital role in the regulation of glucose levels physiological and pathological states such as diabetes mellitus (DM). In type-2 DM (T2DM), insulin resistance causes hyperglycaemia further distortion metabolism.

Seasonal variation in blood pressure (BP) has been observed in different populations. However, only few studies have focused on BP seasonality in diabetic patients. This study examined the seasonal patterns in BP in 62,589 patients with type 1 diabetes mellitus (T1DM) and in 99,546 patients with type 2 diabetes mellitus (T2DM) from the German/Austrian Diabetes Follow-up Registry. Adjusted mean ...