This paper discusses and optimizes an HMM/GMM based User-Customized Password Speaker Verification (UCP-SV) system. Unlike text-dependent speaker verification, in UCP-SV systems, customers can choose their own passwords with no lexical constraints. The password has to be pronounced a few times during the enrollment step to create a customer dependent model. Although potentially more “user-friend...

The purpose of this study was to determine whether chronic cold exposure would increase the aerobic capacity of skeletal muscle in UCP-dta mice, a transgenic line lacking brown adipose tissue (BAT). Wild type and UCP-dta mice were acclimated to either warm (23 °C), or cold (4 °C) conditions. Cold increased muscle oxidative capacity nearly equivalently in wild-type and UCP-dta mice, but did not ...

The production of reactive oxygen species (ROS) in mitochondria is very sensitive to the proton motive force and may be decreased by mild uncoupling, mediated e.g. by mitochondrial uncoupling proteins (UCPs). UCPs were conversely hypothesized to be activated by ROS. Conclusions from experiments studying the reactive product of lipid peroxidation 4-hydroxy-2-nonenal (HNE) in isolated mitochondri...

The uncoupling protein (UCP) of brown adipose tissue is a regulated proton carrier which allows uncoupling of mitochondrial respiration from ATP synthesis and, therefore, dissipation of metabolic energy as heat. In this article we demonstrate that, when UCP is expressed in Saccharomyces cerevisiae, it retains all its functional properties: proton and chloride transport, high-affinity binding of...

We present a plan representation and a generalized algorithm template, called UCP, for unifying the classical plan-space and state-space planning approaches within a single framework. UCP models planning as a process of refining a partial plan. The plan-space and state-space planning approaches are cast as complementary refinement strategies operating on the same partial plan representation. UC...

OBJECTIVE Orexigenic neuropeptide Y (NPY) and dynorphin (DYN) regulate energy homeostasis. Single NPY or dynorphin deletion reduces food intake or increases fat loss. Future developments of obesity therapeutics involve targeting multiple pathways. We hypothesised that NPY and dynorphin regulate energy homeostasis independently, thus double NPY and dynorphin ablation would result in greater weig...

Ellacott, Kate L. J., Catherine B. Lawrence, Lynn E. Pritchard, and Simon M. Luckman. Repeated administration of the anorectic factor prolactin-releasing peptide leads to tolerance to its effects on energy homeostasis. Am J Physiol Regul Integr Comp Physiol 285: R1005–R1010, 2003; 10.1152/ajpregu.00237.2003.—Central administration of a single dose of prolactin-releasing peptide (PrRP) causes a ...

The research work is an extension of the original UCP Model for software estimation by incorporating the factors that are currently weighted in estimation of software by IT professionals. The rationale of the study is to make UCP Model effective, realistic and more accurate for the current IT industry. To identify the gap between the original UCP model and the current estimation considerations,...

BACKGROUND Pouchitis occurs in up to 50% of patients with ulcerative colitis (UC) undergoing ileal pouch anal anastomosis (IPAA). Pouchitis rarely occurs in patients with familial adenomatous polyposis (FAP) who undergo IPAA. Our aim was to compare mucosal and luminal flora in patients with UC-associated pouchitis (UCP), healthy UC pouches (HUC), and healthy FAP pouches (FAP). METHODS Ninetee...

Tumor cells can adapt to a hostile environment with reduced oxygen supply. The present study aimed to identify mechanisms that confer hypoxia resistance. Partially hypoxia/reoxygenation (H/R)-resistant proximal tubular (PT) cells were selected by exposing PT cultures to repetitive cycles of H/R. Thereafter, H/R-induced changes in mRNA and protein expression, inner mitochondrial membrane potenti...