Serum glutamic oxalacetic transaminase (G-OT), glutamic-pyruvic transaminase (G-PT), and isocitric dehydrogenase (ICD) have been estimated in six groups of subjects, namely, normal British adults, normal Nigerian adults, undernourished Nigerian adults and children, Nigerian children with florid protein malnutrition (kwashiorkor), and cases of protein malnutrition after treatment. The normal ran...

Rats given 50% and 25% of their ad lib food intake were taken as undernourished, while those on ad lib intake served as controls. Water was given ad lib for all rats. Body weight of all rats was measured daily. It showed decrease in undernourished groups but not to the extent expected from calorie intake. Fifty tiny (1-2 mm) orange coloured plastic markers mixed with food were given to all rats...

OBJECTIVES To determine the morbidity pattern of asthma in children attending the paediatric asthma follow-up clinic. MATERIALS AND METHODS Longitudinal prospective follow up of hundred and four patients, diagnosed as asthma, over a period of 2 years was done. Regular follow up by the same person during each visit and proper supervision of standard treatment along with parental education rega...

Forty patients with Crohn's disease were divided into undernourished (18) and well nourished (22) groups depending on whether their midarm circumference was below or above 90% of the ideal standard. Plasma 25-(OH)D3 and the dihydroxylated metabolites, 24,25-(OH)2D3 and 1,25-(OH)2D3 were measured in the summer. Results were related to clinical and biochemical parameters and also compared with re...

Undernutrition elicited by a low-protein diet determines a marked reduction of hypophyseal activity and affects the function of the respective target organs. The objective of the present investigation was to study the ultrastructural and quantitative immunohistochemical changes of the different pituitary cell populations in undernourished monkeys that had been previously shown to have significa...

Undernutrition is common in surgical patients, is frequently unrecognised and is strongly associated with adverse outcomes such as high rates of complications and mortality, worsening functional status and prolonged hospitalisation. Owing to the associated infection and symptoms such as repeated vomiting, a high prevalence of undernutrition is expected in hydrocephalus patients, which may contr...

BACKGROUND & AIMS Little is known about the nutritional status of critically ill children during hospitalisation in and after discharge from an intensive care unit. We set up a prospective, observational study to evaluate the nutritional status of children in an intensive care unit from admission up to 6 months after discharge. A secondary aim was identifying patient characteristics that influe...

A study was conducted in Simanjiro district in northern Tanzania to determine the nutritional status of underfive children in a pastoral community. Weight and height measurements were carried out on 250 children and that of mean upper arm circumference (MUAC) on 226 children. The z-scores of weight-for-age, weight-for-height and height-for-age indicated that 31.2% of the children were underweig...

Alterations in autonomic nerve activity in subjects in a chronically undernourished state have been proposed, but have been inadequately documented. The present study evaluated heart rate and systolic blood pressure variability in the frequency domain in two underweight groups, one of which was undernourished and recruited from the lower socio-economic strata [underweight, undernourished (UW/UN...

OBJECTIVE To describe the clinical profile of children with bacteriologically confirmed tuberculosis. STUDY DESIGN A multicentric study was conducted in three hospitals in Chennai city between July 1995 and December 1997. Children aged 6 months to 12 years with signs and symptoms suggestive of tuberculosis were investigated further. Clinical examination, chest radiograph, tuberculin skin test...