Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a lipid and protein phosphatase, and both activities are necessary for its role as a tumour suppressor. PTEN activity is controlled by phosphorylation of its intrinsically disordered C-terminal tail. A recently discovered variant of PTEN, PTEN-long (PTEN-L), has a 173-residue N-terminal extension that causes PTEN-L to exhibit u...

The subject under study is an open subsystem of a larger linear and conservative system and the way in which it is coupled to the rest of system. Examples are a model of crystalline solid as a lattice of coupled oscillators with a finite piece constituting the subsystem, and an open system such as the Helmholtz resonator as a subsystem of a larger conservative oscillatory system. Taking the vie...

The subject under study is an open subsystem of a larger linear and conservative system and the way in which it is coupled to the rest of system. Examples are a model of crystalline solid as a lattice of coupled oscillators with a finite piece constituting the subsystem, and an open system such as the Helmholtz resonator as a subsystem of a larger conservative oscillatory system. Taking the vie...

The subject under study is an open subsystem of a larger linear and conservative system and the way in which it is coupled to the rest of system. Examples are a model of crystalline solid as a lattice of coupled oscillators with a finite piece constituting the subsystem, and an open system such as the Helmholtz resonator as a subsystem of a larger conservative oscillatory system. Taking the vie...

Three visual-search experiments tested whether the preattentive parallel stage can~=seleet-ively guide the attentive stage to a particular known-to-be-relevant target feature. Subjects searched multielement displays for a salient green circle that had a unique form when surrounded by green nontarget squares or had a unique color when surrounded by red nontarget circles. In the distractor condit...

The cardiac troponin I (cTnI) isoform contains a unique N-terminal extension that functions to modulate activation of cardiac myofilaments. During cardiac remodeling restricted proteolysis of cTnI removes this cardiac specific N-terminal modulatory extension to alter myofilament regulation. We have demonstrated expression of the N-terminal-deleted cTnI (cTnI-ND) in the heart decreased the devel...

We unveil new results based on measurement that guarantee the existence of unique xed points which need not be maximal. In addition, we establish that least xed points are always attractors in the topology, and then explore the consequences of these ndings in analysis. In particular, an extension of the Banach xed point theorem on compact metric spaces 3] is obtained.

We consider an o-minimal expansion M0 = (R0, <,+, · · · ) of a real closed field, and a real closed field R, complete in the sense of D. Scott, containing R0 as a dense subfield. We show that M0 has an elementary extension M = (R,<,+, · · · ) with domain R. Moreover, such a structure M with domain R is unique.

An extension of the General and Rapid Association Study Engine (GRASE), a Semantic Web data (entity) prioritisation engine, is discussed. The GRASE employs a unique mechanism to prioritise entities using entitydocument relations by computing the statistical significance between entities and user keywords based on the number of related documents. We describe an improvement of prioritisation accu...