The effects of uridine(UR) on the cell-killing activity of cytosine arabinoside(ara-C) against human leukemic cells, MOLT-4, and on ara-C accumulation in cells were studied. The 50% lethal dose(LD50) of ara-C as determined by clonogenic assay was decreased to 5.0 x 10(-8) mol from 9.0 x 10(-7) mol after 3 days exposure to 10(-3) mol of UR. The accumulation of 3H-ara-C at 24 and 48 h was signifi...

The Lie algebra su(2) of the classical group SU(2) is built from two commuting quon algebras for which the deformation parameter is a common root of unity. This construction leads to (i) a not very well-known polar decomposition of the generators J− and J+ of the SU(2) group, with J+ = J † − = HUr where H is Hermitean and Ur unitary, and (ii) an alternative to the {J2, Jz} quantization scheme, ...

BACKGROUND The Risk Evaluation and Mitigation Strategy (REMS) for retigabine/ezogabine (RTG/EZG) required an evaluation of the effectiveness of the communication plan to communicate about the risks with use of RTG/EZG. OBJECTIVE GlaxoSmithKline conducted a survey to assess understanding of the risk of urinary retention (UR) with RTG/EZG and to evaluate the effectiveness of the communication p...

After beginning with a short historical review of the concept of displaced (coherent) and squeezed states, we discuss previous (often forgotten) work on displaced and squeezed number states. Next, we obtain the most general displaced and squeezed number states. We do this in both the functional and operator (Fock) formalisms, thereby demonstrating the necessary equivalence. We then obtain the t...

Conventional face super-resolution methods, also known as face hallucination, are limited up to 2∼4× scaling factors where 4 ∼ 16 additional pixels are estimated for each given pixel. Besides, they become very fragile when the input low-resolution image size is too small that only little information is available in the input image. To address these shortcomings, we present a discriminative gene...

For many classes of symplectic manifolds, the Hamiltonian flow of a function with sufficiently large variation must have a fast periodic orbit. This principle is the base of the notion of Hofer-Zehnder capacity and some other symplectic invariants and leads to numerous results concerning existence of periodic orbits of Hamiltonian flows. Along these lines, we show that given a negatively curved...

The integration of heterogeneous networks is a trend of Fourth Generation (4G) systems. But with more integrating network technologies, bandwidth management is more complicated. This paper proposes a bandwidth management method, called Bandwidth Management and Disposition (BMD). The BMD calculates the Reword Point (RP) to quantify the Mobile Host’s (MH) requests, and calculates the Upgrade Rank...

In this paper we describe a method for learning grammars in the general framework of Harmonic Serialism (see McCarthy this volume for references and an introduction). We have two main goals. The first is to address the hidden structure problem that serial derivations introduce. The second is to address the problem of learning variation, which has yet to be confronted in this framework (see also...