This study aimed to identify the mechanism(s) for impairment of spermatogenesis in adulthood in rats treated neonatally with estrogens. Rats were treated (days 2-12) with 10, 1, or 0.1 microg diethylstilbestrol (DES), 10 microg ethinyl estradiol (EE), 10 mg/kg of a GnRH antagonist (GnRHa), or vehicle and killed in adulthood. DES/EE caused dose-dependent reductions in testis weight, total germ c...

Background: Premature ovarian failure (POF) is defined by the association of amenorrhea, hypoestrogenism and elevated (menopausal) levels of serum gonadotropins before age of 40 years-old. This condition affects approximately %1 of women under 40 years of age. Physiologic replacement of ovarian steroid hormones seems rational until the age of normal menopause. Temporary return of ovarian functi...

Patients with peripheral neuropathy have symptoms involving small-diameter nociceptive nerves and elevated thermal thresholds. Nociceptive nerves terminate in the epidermis of the skin and are readily demonstrated with the neuronal marker, protein gene product 9.5 (PGP 9.5). To investigate the pathological characteristics of elevated thermal thresholds, we performed PGP 9.5 immunocytochemistry ...

LHRH-stimulated LH and FSH secretion was studied in hemipituitaries, in vitro, obtained from several dystrophic mouse mutants (male : 129/ReJ-dy ; 129B6F1/J\x=req-\ dy; C57BL/6J-dy and C57BL/6J-dy2J; female: 129B6F1/J-dy)and a dystrophic hamster mutant (male and female CHF-147). Without exception, pituitary tissue from dystrophic animals released significantly more FSH than did tissue obtained ...

1. Antler cycles of six adult male axis deer of southern Texas were relatively well synchronized within the herd. The old antlers were cast from December to March and regenerated antlers polished between March and June. The rutting season occurred in June and July. 2. LH and FSH exhibited little seasonal variation (LH 0.7-1.3 ng/ml; FSH 32-65 ng/ml). Prolactin levels were lowest in December (20...

Background: Electromagnetic radiation has different effects on body organs, including gonads and fertility. Information about the harmful impacts of Wi-Fi oxidant-antioxidant system ovarian tissue is limited. Objectives: Therefore, present study aimed to evaluate influence eight weeks aerobic exercise along with garlic supplements levels superoxide dismutase (SOD), malondialdehyde (MDA), glutat...

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women reproductive age group. PCOS has been frequently associated with insulin resistance and obesity. Although cases are obese or overweight, a significant proportion patients have normal body mass index (BMI≤25 kg/m2) that makes diagnostic work up therapeutic approach more difficult. These referred t...

Given a standard Brownian motion B, we show that the equation Xt = x0 + Bt + β(Lt ) , t ≥ 0 , has a unique strong solution X. Here L is the symmetric local time of X at 0, and β is a given differentiable function with β(0) = 0, −1 < β′(·) < 1. (For linear β(·), the solution is the familiar skew Brownian motion).