many studies with different results have been conducted regarding varicocelectomy in patients with subclinical varicocele and its effect on semen parameters. this clinical trial was aimed at assessing the effect of varicocelectomy on the spermiogram of patients with subclinical varicocele. a total of 142 patients with varicocele (79 clinical and 63 subclinical) took part in the study. two sperm...

Varicocele repair is mainly indicated in young adult patients with clinical palpable varicocele and abnormal semen parameters. Varicocele treatment is associated with a significant improvement in sperm concentration, motility, morphology, and pregnancy rate. Antegrade scrotal sclerotherapy (ASS) represented one of the main alternatives to the traditional inguinal or suprainguinal surgical ligat...

A consensus needs to be reached on a rational approach to infertile men with varicocele-associated nonobstructive azoospermia. Future studies are warranted to understand the mechanism behind the variable influence of varicocele on testicular function, which causes partial or complete damage of spermatogenesis in some cases and leaves it unaltered in others.

Varicocele affects approximately 35%-40% of men presenting for an infertility evaluation. There is fair evidence indicating that surgical repair of clinical varicocele improves semen parameters, decreases seminal oxidative stress and sperm DNA fragmentation, and increases the chances of natural conception. However, it is unclear whether performing varicocelectomy in men with clinical varicocele...

Varicocelectomy is the most commonly performed operation for the treatment of male infertility. Varicocele is found in approximately 15% of general male population and in 40% of men with infertility. The treatment of varicocele is not necessary unless the varicocele causes pathological spermiogram, difficulties and intense testicular volume at work and walking, also in children with varicocele ...

BACKGROUND Varicocele is a bilateral vascular disease, involving a network of collaterals and small, retroperitoneal bypasses. The right and the left testicular venous drainage systems are complex and not identical to each other. It was considered a predominantly unilateral (left-sided) disease. Its pathophysiology has not been clearly delineated and the treatments offered do not seem to be eff...

A varicocele is described as pathologically enlarged, tortuous veins of the pampiniform plexus, leading to an increased testicular temperature and adrenal metabolite reflux into the testes. Varicocele can impair spermatogenesis and is considered to be the most common cause of male infertility. Patients may palpate a thickening in the scrotum or complain of dull scrotal or inguinal pain, which i...

Varicocele is most often surgically repaired due to male infertility, however, has recently been linked to low serum testosterone. This paper serves to review the current literature regarding varicocele and its subsequent repair on serum testosterone. Twenty-eight human studies were identified with fifteen showing improved serum testosterone after repair. The majority of the studies that demons...

The role of varicoceles in the etiology of male infertility continues to be controversial. Due to the numerous variables that impact the outcome of varicocele surgery, the results of various trials are often contrary. Recent studies at the molecular level have demonstrated that varicoceles can cause testicular nuclear DNA damage, apoptosis, and raised levels of reactive oxygen species. Clinical...