Vascular brain diseases are one of the leading causes death and disability in developed countries. Along with acute disorders cerebral circulation, chronic cerebrovascular great medical social importance, main clinical manifestations is vascular cognitive impairments. The article discusses pathogenetic variants impairments, presents their modern classification approaches to diagnosis. importanc...

Background Anti-β2GPI-Domain 1 (β2GPI-D1) antibodies are potentially pathogenic in patients with antiphospholipid syndrome (APS), but their clinical associations and diagnostic value were unclear. Objectives To evaluate the characteristics of APS anti-β2GPI-D1 positivity, its utility diagnosing among SLE patients. Methods A total 338 included, which 169 diagnosed primary (PAPS group), 50 second...

objective: to evaluate the predictive value of some biochemical markers in the outcome of extremity vascular trauma. methods: this study comprised 30 patients with traumatic arterial injury and acute limb ischemia referred to namazi hospital affiliated with shiraz university of medical ssciences, over a period of 8 months, from sep 2009 to jul 2010. venous blood samples were drawn from distal i...

OBJECTIVE To use magnetic resonance imaging to identify vascular loops in the anterior inferior cerebellar artery and to evaluate their relationship with otologic symptoms. MATERIALS AND METHODS We selected 33 adults with otologic complaints who underwent magnetic resonance imaging at our institution between June and November 2013. Three experienced independent observers evaluated the traject...

Diabetic cerebrovascular diseases are defined as cerebral vascular diseases induced by diabetes with sugar, fat and a series of nutrient substance metabolic disorders, resulting in intracranial large and small vessel diseases. About 20%-40% patients with type 2 diabetes suffer from cerebral blood vessel diseases. Diabetic cerebrovascular diseases are the main causes of death in patients with di...

OBJECTIVE To analyze primary intra- and juxta-articular vascular malformations of the temporomandibular joint. PATIENTS AND METHODS This study retrospectively reviewed eight patients (seven venous malformations and one lymphatico-venous malformation) who were treated for intra- or juxta-articular vascular malformations of the temporomandibular joint from November 2005 to January 2011. All pat...

INTRODUCTION Patients with rheumatoid arthritis (RA) are at an increased risk for cardiovascular disease (CVD). One of the earliest manifestations of CVD is endothelial dysfunction (ED). ED can occur in both the microcirculation and the macrocirculation, and these manifestations might be relatively independent of each other. Little is known about the association between endothelial function in ...

Systemic sclerosis (SSc) is a complex and heterogeneous chronic illness characterized by substantial patient to patient variability in clinical manifestations, internal organ involvement, and outcome. Genetic factors contribute to disease susceptibility, but environmental influences also play a significant role. The pathogenesis of SSc encompasses vascular, immunological, and fibrotic processes...

Behcet’s disease, a systemic vasculitis of unknown etiology, is characterized by recurrent oral and genital ulcers, ocular manifestations and skin lesions.1 Cardiovascular manifestations may occur in around 7-38% of patients;1 it is, thus, the most common cause of death among these patients.2 Peripheral vascular lesion is rare, and arterial lesions are less common than venous disease; its preva...

Loss of cognitive function is one the most devastating manifestations of ageing and vascular disease. Cognitive decline is rapidly becoming an important cause of disability worldwide and contributes significantly to increased mortality. There is growing evidence that hypertension is the most important modifiable vascular risk factor for development and progression of both cognitive decline and ...