Diab b b b b b bet et et et et et etes es es es es es s I I I I I I Ins ns ns ns ns ns nsti ti ti ti ti ti titu tu tu tu tu tu tute y, Abstract: Background-The pathophysiology of vasovagal syncope (VVS) is poorly understood and the

vasovagal syncope or neurocardiogenic syncope refers to the loss of consciousness that occurs secondary to hypotension resulting in reduced blood supply to the brain. it is the most common form of unexplained syncope (50-60%) in the outpatient setting. Bradycardia and vasodilation are the primary causes of this hypotension. fear, pain, dehydration, alcohol consumption, anxiety, tight clothing a...

OBJECTIVE To investigate whether the electrocortical activity underlying the anticipation and processing of emotional stimuli is enhanced in individuals with recurrent episodes of vasovagal syncope (VVS). METHODS Fifteen fainters and 15 age-matched healthy controls were presented a S1-S2 task, where the content of high-arousal pleasant and unpleasant, and neutral pictures (S2) was forecasted ...

The aim of this retrospective study (February 2012-September 2014) was to assess the role of head-up tilt-table test in patients with unexplained syncope. It was performed on 235 patients at Clinical Department of Cardiology, Sestre milosrdnice University Hospital Center. Patients were classified according to test indications: group A (convulsive syncope, n = 30), group B (suspected vasovagal s...

BACKGROUND Most subjects with blood/injury phobia experience syncope or presyncope as part of the phobic response. We tested the hypothesis that these subjects have a constitutional autonomic dysregulation that predisposes them to vasovagal syncope during head-up tilt. METHODS AND RESULTS We studied 11 subjects (9 females, 2 males) who had a history of syncope or presyncope only in response t...

INTRODUCTION Numerous hormones, neurotransmitters, and other stimuli exert their biological effect on cellular functioning through heptahelical receptors coupled to G proteins (GPCR - G protein-coupled receptors). Adrenergic receptors that belong to this superfamily of receptors are components of the sympathetic nervous system. They play a pivotal role in blood pressure regulation and myocardia...

Orthostatic hypotension (OH) occurs in 0.5% of individuals and as many as 7-17% of patients in acute care settings. Moreover, OH may be more prevalent in the elderly due to the increased use of vasoactive medications and the concomitant decrease in physiologic function, such as baroreceptor sensitivity. OH may result in the genesis of a presyncopal state or result in syncope. OH is defined as a...