Removal of the white cells and platelets from suspensions of red cells usually produces substantial reduction in the hemolytic activity of venoms. Guinea pig red cells constitute a notable exception and may be lysed by a direct action of venom. White blood cells and platelets appear to contribute to hemolysis by serving as sources of phosphatides for the formation of lysophosphatides. No correl...

In the present study an ELISA assay was developed and validated for detection determination of concentration snakes venom in biological samples. Individual component each (Cerastes cerastes Macrovipera mauretanica) used as immunogen to raise specific rabbit IgGs order set up a sandwich-type ELISA. Lower limit, linearity, accuracy, precision, reproducibility, reference intervals were determined....

Objective: The aim of this study was to analyze current evidence regarding allergy to Hymenoptera venoms. Brief review: The Hymenoptera species, which are most important in the context of venom allergy, include the common wasp (Vespula vulgaris), German wasp (Vespula germanica), and the honey bee (Apis mellifera). Depending on the population, systemic allergic reactions occur in 1.5–8.9% of cas...

The Indian cobra?Naia naia vel tripudians varies from 100 to 150 cm. in length and has a variable colour but is usually black. The head is generally golden yellow in colour, spotted with yellowish white marks above and pure white beneath. The species is distributed throughout the whole of Southern Asia from the south of the Caspian Sea to the south of China, India, Burma., Ceylon and the Malay ...

In Venezuela, Bothrops snakes are responsible for more than 80% of all recorded snakebites. This study focuses on the biological and hemostatic characteristics of Bothrops isabelae venom along with its comparative characteristics with two other closely related Bothrops venoms, Bothrops atrox and Bothrops colombiensis. Electrophoretic profiles of crude B. isabelae venom showed protein bands betw...

During the past few years a great deal of interest has been taken in the use of snake venoms in medical treatment. The results obtained in a series of cases treated in the Carmichael Hospital and School of Tropical Medicine, Calcutta, have been reported previously by the present authors (Chopra and Chowhan, 1937). Since then, the opportunity for treating a large number of patients suffering fro...

Snake venoms are complex toxin mixtures. Viperidae and Crotalidae venoms, which are hemotoxic, are responsible for most of the envenomations around the world. Administration of antivenins aimed at the neutralization of toxins in humans is prone to potential risks. Neutralization of snake venom toxins has been achieved through different approaches: plant extracts have been utilized in etnomedici...

Parasitoid wasps are valuable biological control agents that suppress their host populations. Factors introduced by the female wasp at parasitization play significant roles in facilitating successful development of the parasitoid larva either inside (endoparasitoid) or outside (ectoparasitoid) the host. Wasp venoms consist of a complex cocktail of proteinacious and non-proteinacious components ...

Aqueous extracts of Mucuna pruriens seeds were tested for their activity on various pharmacological effects like lethality, phospholipase activity, edema forming activity, fibrinolytic activity and haemorrhagic activity of of cobra and krait venoms. The aqueous extract displayed a significant inhibitory effect on the lethality, phospholipase activity, edema forming activity, fibrinolytic activi...

Venoms are produced by a wide variety of species including spiders, scorpions, reptiles, cnidarians, and fish for the purpose of harming or incapacitating predators or prey. While some venoms are of relatively simple composition, many contain hundreds to thousands of individual components with distinct pharmacological activity. Pain-inducing or "algesic" venom compounds have proven invaluable t...