background: dextrocardia is a congenital anomaly, which may have coexistent coronary artery disease (cad), arrhythmias and conventional indications for device therapy. however, the implantation of transvenous leads can be technically challenging and the approach needs to be tailored to the patient's individual anatomy. case presentation: a 54-year-old male with dextrocardia situs inversus ...

Coronary artery narrowing, ranging from 19% to 61%, was induced in rats and ventricular performance, myocardial damage, and myocyte hypertrophy were examined 1 mo later. Animals were separated into two groups, exhibiting ventricular dysfunction and failure, respectively. Dysfunction consisted of a 2.4-fold increase in left ventricular end diastolic pressure (LVEDP), 15% decrease in left ventric...

Right ventricular dysfunction is not uncommon in adults with congenital heart disease. In congenital heart disease, unlike acquired heart disease, the right ventricle is not always the subpulmonary ventricle: it may support the systemic circulation as it does in patients with transposition complexes. The result is chronic right ventricular pressure overload. In contrast, pulmonary valve regurgi...

coronary artery disease is one of the most common causes of mortality and morbidity across the world. its treatment includes medical treatment, coronary artery bypass graft (cabg) and percutaneous coronary intervention (pci). the purpose of this study was to investigate the effect of pci on echocardiographic findings of left ventricular (lv) systolic and diastolic function. 115 patients with co...

BACKGROUND A significant proportion of myocardial infarction (MI) patients undergo complex, coordinated perturbations at the molecular level that may eventually drive the occurrence of ventricular dysfunction and heart failure. Despite advances in the elucidation of key processes implicated in this condition, traditional methods relying on gene expression data and the identification of individu...

We report on a 44-year-old woman presenting with chest pain and dyspnoea without previous stress-related events. By means of echocardiography severe left ventricular dysfunction and wall motion abnormalities resembling stress-induced cardiomyopathy (Tako Tsubo) were seen. Laboratory investigation revealed thyrotoxicosis and elevated cardiac markers. Six days after starting medical treatment, co...

Ventricular dysfunction remains a hallmark of most cardiac disease. The mouse has become an essential model system for cardiovascular biology, and echocardiography an established tool in the study of normal and genetically altered mice. This review describes the measurement of ventricular function, most often left ventricular function, by echocardiographic methods in mice. Technical limitations...

In patients with coronary artery disease, one of the most powerful determinants of prognosis is left ventricular function. 2 Thus, if we assume that the prognostic benefit of revascularisation is mediated through an eVect on left ventricular function, two mechanisms might explain this benefit. First, coronary artery bypass surgery or angioplasty could reduce the impact of coronary artery diseas...

Background: The purpose of this study was to investigate efficacy of high dose vitamin D in improving left ventricular ejection fraction (LVEF) in thalassemia patients with heart failure and vitamin D deficiency. Materials and Methods: This clinical trial study was conducted on 16 chronically transfused thalassemia patients and ventricular dysfunction with vitamin D deficiency between December...