BACKGROUND Vesicoureteral reflux (VUR) is a common childhood disorder that is characterized by the abnormal movement of urine from the bladder into the ureters or kidneys. OBJECTIVES The aim of this study was to determine whether the genetic polymorphisms of the IL-10, IL-12, and TNF-α genes are involved in the development of VUR. PATIENTS AND METHODS The tetra amplification mutation refrac...

Vesicoureteral reflux (VUR) is common condition in infants with febrile urinary tract infections (UTIs). Both VUR and febrile UTIs are risk factors for renal scars, characterized by glomerular hypertrophy with global or segmental sclerosis as cardinal features in pathology. Because renal scars may cause hypertension or chronic kidney diseases in later life, voiding cystourethrography (VCUG) has...

conclusion our findings showed an increased frequency of vur in patients with bjhms. we suggest that infants and children with bjhms should be screened for vur. results vur was observed in 60% of patients with bjhms. however, sonography was normal in 66.7% of patients. the most common grading of reflux was grade ii of vur (37.5%). seventy percent of patients with bjhms and neurogenic bladder ha...

Background: Experience with vesicoureteral reflux (VUR) differs in different centers and there is plenty of controversies.Objective: To evaluate the outcome of primary VUR complications and the rate of recurrence of UTI.Methods:  In a retrospective study, the medical charts of all infants and children with primary VUR who were followed up by one nephrologist were reviewed.  During 16 years, 271...

BACKGROUND The Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) trial found that recurrent urinary tract infections (rUTI) with resistant organisms were more common in the trimethoprim-sulfamethoxazole prophylaxis (TSP) arm. We describe factors associated with trimethoprim-sulfamethoxazole (TMP-SMX) resistance of rUTIs in RIVUR. METHODS Children aged 2 to 71 months with...

AIM To evaluate the association between primary vesicoureteral reflux (VUR) and renal scarring in children using 99 m Technetium-labelled dimercaptosuccinic acid (DMSA). METHODS Children attending at Songklanagarind Hospital from 1987 to 2002 were evaluated. RESULTS Ages at diagnosis of VUR in 46 boys and 52 girls were 1.1+/-1.6 and 2.9+/-2.5 years, median 0.6 and 2.3 years, respectively (P...

Introduction. Fibroblast growth factor 2 (FGF2) is a potent mitogenic factor of cortical fibroblasts and induces kidney fibrosis. We hypothesized that serum levels of FGF2 has an association with the severity of vesicoureteral reflux (VUR) and renal parenchymal scar. Materials and Methods. Between 2007 and 2009, a total of 28 children with VUR were enrolled in this study and were compared with ...

OBJECTIVE To revise the American Academy of Pediatrics practice parameter regarding the diagnosis and management of initial urinary tract infections (UTIs) in febrile infants and young children. METHODS Analysis of the medical literature published since the last version of the guideline was supplemented by analysis of data provided by authors of recent publications. The strength of evidence s...

Introduction The endoscopic correction of vesicoureteral reflux (VUR) in children is a currently well accepted therapy in many pediatric urology centers. Polyacrylate-polyalcohol copolymer (PPC), namely Vantris®, is one of the tissue-augmenting substances used for endoscopic reflux therapy. The aim of this study was to evaluate the results with PPC in children. Material and methods From 2012 ...