A gene therapy of synovial tissue is potentially a novel therapeutic method in rheumatoid arthritis (RA). The method induces expression of anti-arthritic molecules in target cells, and is also useful for the investigation of novel therapeutic targets in vitro. Previous studies showed that viral vectors, which can infect non-proliferative cells well, i.e. adenovirus-based vector, were effective ...

Hepatitis B virus, hepatitis C virus and human immunodeficiency virus share a similar transmission pathway and are often diagnosed in the same patient. These patients tend to have a faster progression of hepatic fibrosis. This cross-sectional study describes the demographic features and clinical profile of human immunodeficiency virus/hepatitis co-infected patients in Paraná, Southern Brazil. A...

HIV, or human immunodeficiency virus, is a virus that targets the body’s immune system and weakens it so struggles to defend against other pathogens designed harm body. In order enhance health decrease transmission of patients who have HIV are treated with antiretroviral therapy, ART, treatment seeks reduce replication by disrupting specific portion cycle. However, while does vertical between m...