Vitamin B(12) is essential for DNA synthesis and for cellular energy production.This review aims to outline the metabolism of vitamin B(12), and to evaluate the causes and consequences of sub-clinical vitamin B(12) deficiency. Vitamin B(12) deficiency is common, mainly due to limited dietary intake of animal foods or malabsorption of the vitamin. Vegetarians are at risk of vitamin B(12) deficie...

background: hypocalcemia is a well-recognized complication after total thyroidectomy. hypovitaminosis d may have additional effect in the development of hypocalcemia. this study aimed to determine the effect of total thyroidectomy on postoperative serum calcium in patients with and without hypovitaminosis d. methods: this prospective study was performed on patients who underwent total thyroidec...

Aims and method To review the current clinical practice and guidelines for testing and treating vitamin D deficiency in adolescents admitted to a tier 4 adolescent psychiatric unit in north London. The blood test results of 56 patients admitted between 2012 and 2014 were examined to determine whether vitamin D levels had been tested. For those individuals who were tested for vitamin D, results ...

Objective. To compare the prevalence of the vitamin B12 deficiency in geriatric diabetic patients treated with or without metformin. Methods. Records of 134 patients with diabetes mellitus (DM) aged 61 to 93 (mean, 80) years who were treated with (n=56) or without (n=78) metformin were reviewed. Patient demographics (age, gender, duration of DM, smoking status, alcohol consumption), medication ...

Vitamin D is important for the development, growth, and mineralization of the skeletal in neonates and children. Vitamin D is essential for intestinal absorption of calcium. Vitamin D is metabolized to 25-hydroxyvitamin D and then to 1,25-dihydroxyvitamin D. Pregnant women in developed countries often have insufficient serum concentrations of 25-hydroxyvitamin D and a supplementation of vitamin...

Apropos of article on the association between serum vitamin-D and insulin resistance in individuals with prediabetes1, the authors need to be complimented for their effort in establishing vitamin-D deficiency as a predictor for insulin resistance. As pointed out by the authors the study showed that vitamin-D insufficiency/ deficiency was common among individuals with prediabetes. However, there...

OBJECTIVES In the era of combination antiretroviral therapy (cART), vitamin D deficiency, low bone mineral density (BMD) and fractures have emerged as subjects of concern in HIV-positive patients. Testing for vitamin D deficiency has been widely adopted in clinical practice even though the benefits of vitamin D supplementation in this population remain uncertain. The objective of this review wa...

OBJECTIVES Vitamin D has been found to be strongly associated with many systemic disorders. There has been an augmented interest within the medical community in vitamin D, especially its deficiency, in various systemic disorders. Although the role of vitamin D deficiency in irritable bowel syndrome (IBS) has not yet been established, studies are underway to clearly establish its role in the dis...

BACKGROUND Vitamin A deficiency is a risk factor for blindness and for mortality from measles and diarrhoea in children aged 6-59 months. We aimed to estimate trends in the prevalence of vitamin A deficiency between 1991 and 2013 and its mortality burden in low-income and middle-income countries. METHODS We collated 134 population-representative data sources from 83 countries with measured se...

Background: The purpose of this study was to investigate efficacy of high dose vitamin D in improving left ventricular ejection fraction (LVEF) in thalassemia patients with heart failure and vitamin D deficiency. Materials and Methods: This clinical trial study was conducted on 16 chronically transfused thalassemia patients and ventricular dysfunction with vitamin D deficiency between December...