BACKGROUND AND AIM The aim of the study was to evaluate vitamin E effect upon oxidative stress associated with toluene -2, 4-diisocyanate (TDI)-induced asthma in rats. METHODS The five study groups were: control, vehicle, TDI, vehicle+E, TDI+E. TDI animals were sensitized by nasal administration of TDI 10% (5μl/nostril) between days 1-7 and 15-21. Between days 22-28 groups TDI+E and vehicle+E...

background: exposure to sunlight is the main source of vitamin d production. this study was performed to assess the status of serum vitamin d across the different seasons in geographic region of babol, with latitude of 36 in northern iran. methods: the study – female participants were 15 years old and above selected prospectively according to the inclusion criteria who attended an outpatient cl...

background: vitamin d (vit d) is linked to various conditions including musculoskeletal, metabolic and   cardiopulmonary diseases. however, it is not clear whether correction of vit d deficiency exerts any beneficial effect in patients with pulmonary hypertension. methods: this study was a prospective uncontrolled longitudinal study. patients with pulmonary hypertension and vit d deficiency wer...

non:union: is common complication of fracture management. various factors are involved in its occurring. metabolic and endocrine factors are often overlooked. so that aim of study was to evaluate the level of vitamin d and pth in patients with unexplained non:union: and fractures due to low energy trauma. in the case control study, 30 patients with tibial non:union: compared with 32 patients wi...

conclusions the vitamin d levels of children aged more than 2 years are lower than those of children aged less than 2 years. thus, prescribing vitamin d-containing supplements in children older than 2 years may be beneficial. results the final study consisted of 286 children, 140 males and 146 females, with a mean age of 4.46 ± 2.82 yr. of these, 218 (76.22%) children, with a mean age of 5.09 ±...

OBJECTIVE The objective was to provide guidelines to clinicians for the evaluation, treatment, and prevention of vitamin D deficiency with an emphasis on the care of patients who are at risk for deficiency. PARTICIPANTS The Task Force was composed of a Chair, six additional experts, and a methodologist. The Task Force received no corporate funding or remuneration. CONSENSUS PROCESS Consensu...

BACKGROUND Observational data associate lower levels of serum vitamin D with coronary artery calcification, cardiovascular events and mortality. However, there is little interventional evidence demonstrating that moderate vitamin D deficiency plays a causative role in cardiovascular disease. This study examined the cardiovascular effects of dietary vitamin D deficiency and of vitamin D receptor...

1. Rajeswari J, Balasubramanian K, Bhatia V, Sharma VP, Agarwal AK. Aetiology and clinical profile of osteomalacia in adolescent girls in northern India. Natl Med J India. 2003;16:139-42. 2. Delvin EE, Salle BL, Glorieux FH, Adeleine P, David LS. Vitamin D supplementation during pregnancy: Effect on neonatal calcium homeostasis. J Pediatr. 1986;109:32834. 3. Purvis RJ, Barrie WJ, MacKay GS, Wil...

Vitamin E is the primary lipophilic antioxidant in mammals. Lack of vitamin E may lead to an increase of cytotoxic phospholipid-peroxidation products (PL-Ox). However, we could previously show that alimentary vitamin E-depletion in rats did not change the concentrations of dienes, hydroperoxides, and platelet-activating factor-related oxidation products in alveolar type II cells (TII cells). We...