OBJECTIVES The aim of this study was to investigate the clinical characteristics of HAVS in a tropical environment in comparison with a temperate environment. METHODS We conducted a series medical examinations among the forestry, construction and automobile industry workers in Malaysia adopting the compulsory medical examination procedure used by Wakayama Medical University for Japanese vibra...

OBJECTIVES We aimed to determine whether ranirestat, an aldose reductase inhibitor, maintains the improved nerve function observed in patients with diabetic sensorimotor polyneuropathy (DSP) after completing a 12-week nerve biopsy study. RESEARCH DESIGN AND METHODS Patients with mild to moderate DSP, as determined by the presence of sural nerve responses, were enrolled in a double-blind, plac...

Aim: This study compared the levels of dental anxiety experienced by young uncooperative children having dental rehabilitation using general anaesthesia (GA) with those who had their dental treatments by “Tell-ShowDo” technique in the dental clinic. Methods: Out of 54 children, 26 had been treated under GA and 28 had been treated with the use of “Tell-Show-Do” behavioural approach method. At th...

Human breast milk is the ideal nutrition for the newborn, and in addition to its nutritional contribution, necessary for infant growth and development, it contains various immune bioactive factors that confer some of the numerous beneficial effects of breastfeeding. The current study analyzed the concentrations of IgA, growth factors such as epidermal growth factor (EGF), TGFβ1, and TGFβ2, cyto...

The frequency-tagging approach has generally been confined to study low-level sensory processes and always found related activation over the occipital region. Here for the first time, we investigated with it, high-level socio-cognitive functions, i.e. the processing of what other people are looking at which is referred to as level 1 visual perspective taking (VPT). Sixteen participants were pre...

We have constructed a PRC1-SUC2 gene fusion that directs the synthesis in Saccharomyces cerevisiae of a hybrid polypeptide consisting of a 433-residue amino-terminal domain derived from the yeast vacuolar protease carboxypeptidase Y (CPY; EC 3.4.16.1) and a 511-residue carboxyl-terminal domain derived from the secreted yeast enzyme invertase (EC 3.2.1.26). Fractionation data indicated that this...

Computational Grids are emerging as a platform for next-generation parallel and distributed computing. Large-scale parametric studies and parameter sweep applications find a natural place in the Grid’s distribution model. There is little or no communication between jobs. The task of parallelizing and distributing existing applications is conceptually trivial. These properties of parametric stud...

Objective. The aim of this study was to compare SUDOSCAN, a new device to evaluate sweat function (reflecting peripheral small C-fiber status), with conventional measures of peripheral and cardiac neuropathy in patients with type 2 diabetes. Methods. 265 diabetic patients were tested for symptoms and clinical signs of neuropathy using Michigan Neuropathy Screening Instrument (MNSI), vibration p...

Aim: To investigate the effect of normalizing vitamin B12 (B12) levels with oral (methylcobalamin) 1000 ?g/day for one year in patients diabetic neuropathy (DN). Patients and methods: In this prospective, double-blind, placebo-controlled trial, 90 type 2 diabetes on metformin at least four years both peripheral autonomic DN were randomized to an active treatment group (n = 44) receiving a contr...

We are interested in embedding trees T with ∆(T) ≤ 4 a rectangular grid, such that the vertices of correspond to grid points, while edges non-intersecting straight segments lines. Such embeddings called models. While each edge is represented by segment, path model union corresponding its edges, which may consist having several bends. The aim determine given tree minimizing maximum number bends ...