We had 23-year-old women with 5 months pregnancy who presented with acute dyspnea without past medical history of known cardiopulmonary disease and normal physical examination in heart and lung. Acute pulmonary embolism (PE) was diagnosed a er patient undergone V/Q mismatch scan. She was treated with low molecular weight heparin (LMWH) (Enoxaparine Sc) during pregnancy, warfarin a er delivery u...

It is a popular belief, that marijuana smoking is not harmful to health. Some publications, however, suggest its possible association with mental, respiratory and cardiovascular complications, but not with venous thromboembolism. The authors describe a case of severe pulmonary embolism in a mildly obese, 22 year-old marijuana and tobacco smoker. After thrombolysis, rapid haemodynamic improvemen...

Fourteen patients were treated with anticoagulants during 15 pregnancies. Eleven had venous thrombosis, three with pulmonary embolism; three had prosthetic heart valves; and one had mitral stenosis with pulmonary hypertension. AU 15 were treated with heparin and 10 with warfarin. The mean duration of heparin therapy was 4-5 weeks and of warfarin 14 weeks. There were two minor episodes of recurr...

Until recently, warfarin has been the primary treatment of venous thromboembolism (VTE). Limited data are available regarding physician attitudes toward anticoagulant choice in the setting of novel oral anticoagulant (NOAC) availability. This study sought to evaluate attending physician attitudes toward NOACs. A survey was sent to attending physicians from internal medicine (primary care and ho...

OBJECTIVE Patients with venous thromboembolism (VTE) often require temporary warfarin interruption for an invasive procedure. The incidence of thromboembolism and bleeding related to periprocedural anticoagulation management of such patients is unknown. METHODS AND RESULTS In a protocol-driven, inception cohort design study, all VTE patients (n=775) referred for periprocedural anticoagulation...

Objective—Patients with venous thromboembolism (VTE) often require temporary warfarin interruption for an invasive procedure. The incidence of thromboembolism and bleeding related to periprocedural anticoagulation management of such patients is unknown. Methods and Results—In a protocol-driven, inception cohort design study, all VTE patients (n 775) referred for periprocedural anticoagulation m...

OBJECTIVE To assess the risk of venous thromboembolism in women using hormone replacement therapy by study design, characteristics of the therapy and venous thromboembolism, and clinical background. DESIGN Systematic review and meta-analysis. DATA SOURCES Medline. STUDIES REVIEWED Eight observational studies and nine randomised controlled trials. INCLUSION CRITERIA Studies on hormone re...

INTRODUCTION Despite evidence-based guidelines for venous thromboembolism prevention, substantial variability is found in practice. Many economic evaluations of new drugs for thromboembolism prevention do not occur prospectively with efficacy studies and are sponsored by the manufacturers, raising the possibility of bias. We performed a systematic review of economic analyses of venous thromboem...

The efficacy and safety of direct oral anticoagulants (DOAC) with antiplatelet therapy compared to warfarin are unclear. The subjects were 280 patients who received antiplatelet therapy with oral anticoagulation (OAC) for the treatment of or protection from thromboembolism between January 2012 and September 2015. Among the 280 subjects, 79 (28.2%) received dual therapy (OAC plus aspirin or P2Y1...

introduction: oral contraceptives (ocs) are considered as one of the most common risk factor of venous thromboembolism (vte) in child bearing age. some of the recent researches indicate that the odds of vte may be even higher with newer generations of ocs. the present meta-analysis was designed to evaluate the effect of different generation of ocs on the occurrence of vte. methods: two research...