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OBJECTIVE The PREDG trial was designed to study the influence of an educative program on gestational weight gain in women with pregestational obesity. METHODS Randomized controlled clinical (https://www.isrctn.com/ISRCTN61793947) 169 obesity (BMI ≥30 kg/m2). Women were randomized participate a group education nutrition and physical activity or conventional follow-up specialized Unit Obesity Pre...
OBJECTIVE Studies in type 2 diabetes report both increased mortality for normal weight and no evidence of an obesity paradox. We aimed to examine whether adipose tissue, muscle size, and physical function, which are known to vary by weight, mediate associations between BMI and mortality. RESEARCH DESIGN AND METHODS The AGES-Reykjavik cohort comprised participants aged 66-96 years with diabete...
BACKGROUND It has been known for a long time that use of antipsychotics, particularly atypical antipsychotics, is associated with weight gain and increase in risk of metabolic disturbances. In this study we have tried to find out if use of antipsychotics is associated with increase in weight and body mass index (BMI) in the Pakistani population. METHODS We performed a case note review of all ...
BACKGROUND The obesity has achieved an alarming increase in recent years, which led this disease to global epidemic condition. AIM To evaluate the nutritional status as well as the quality of life of obese patients undergoing bariatric surgery. METHODS A transversal study was conducted with obese adults of both genders who underwent bariatric surgery by Fobi-Capella technique for at least 3...
BACKGROUND The aim of this study was to examine factors influencing plasma concentration of efavirenz and nevirapine. METHODS Data from the Liverpool Therapeutic Drug Monitoring (TDM) registry were linked with the UK Collaborative HIV Cohort (CHIC) Study. For each patient, the first measurement of efavirenz (600 or 800 mg/day) or nevirapine (400 mg/day) plasma concentration was included. Line...
Risk factors and outcomes of fetal macrosomia in a tertiary centre in Tanzania: a case-control study
BACKGROUND Fetal macrosomia is defined as birth weight ≥4000 g. Several risk factors have been shown to be associated with fetal macrosomia. There has been an increased incidence of macrosomic babies delivered and the antecedent complications. This study assessed the risk factors, maternal and neonatal complications of fetal macrosomia in comparison with normal birth weight neonates. METHODS ...
UNLABELLED The quality of (18)F-FDG PET/CT images of overweight patients is often degraded. We evaluated the effect of optimizing injected dose or acquisition time on the quality of images of overweight patients using lutetium oxyorthosilicate PET/CT with high-performance detector electronics. METHODS We initially retrospectively measured radioactivity concentrations and signal-to-noise ratio...
Obesity is becoming increasingly common and recognized as a major public health problem worldwide. It is associated with multiple chronic health conditions including heart disease, hypertension, hyperlipidemia, diabetes, hyperinsulinemia, and cancer. The present investigation aims to determine i) the effect of using a mixture of natural herbs (Mallow, Senna and Sage) on weight loss in overweigh...
OBJECTIVE To evaluate the first phase of a specialist weight management programme provided entirely within the UK National Health Service. DESIGN Prospective cohort study using multiple logistic regression analysis to report odds of ≥5 kg weight loss in all referrals and completers, and odds of completion, with 95 % confidence intervals. Anxiety and depression 'caseness' were measured by the ...
Newborn weight exceeding 4000 g or 4500 is considered as macrosomia, incidence of which varies from 6 to 10% all deliveries. Maternal diabetes, obesity, age >35 years, male baby, history previous multiparity are few risk factors. It associated with several maternal and neonatal complications presents an obstetric challenge there no consensus regarding the most appropriate route delivery for ...
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