Background and Aim: Restoration of endodontically treated teeth is one of the most important and challenging topics in restorative dentistry. Longevity of such restorations is an essential factor in treatment planning. Amalgam build-up is a conservative method for restoration of endodontically treated teeth. Therefore, this study aimed to assess the longevity of this type of restoration in endo...

Exercise is a common component of weight loss strategies, yet exercise programs are associated with surprisingly small changes in body weight [1-4]. This may be due in part to compensatory adaptations, in which calories expended during exercise are counteracted by decreases in other aspects of energy expenditure [1, 5-10]. Here we examined the relationship between a rodent model of voluntary ex...

Calorie restriction (CR) robustly extends the lifespan of numerous species. In the yeast Saccharomyces cerevisiae, CR has been proposed to extend lifespan by boosting the activity of sirtuin deacetylases, thereby suppressing the formation of toxic repetitive ribosomal DNA (rDNA) circles. An alternative theory is that CR works by suppressing the TOR (target of rapamycin) signaling pathway, which...

The purpose of this study is to investigate possible influences of different stressors (saline injections, light deprivation and constant light regimen) and geroprotectors (Epitalon and melatonin) on survivals of female HER-2/neu transgenic mice. We propose a semi-parametric model of heterogeneous mortality (frailty model) for the analysis of the experimental data. In this model, we assume that...

this research explores the possible benefits to be derived from interactions between wheels, for supporting a greater proportion of applied loads in the shallower soil layers. this creates possibilities for reducing the risk of deep soil compaction. previous research indicated that different interaction modes occurred under simulated wheel arrangements, being mostly dependent upon the spacing b...

the prey suitability for generalist predators is an important feature for efficient mass rearing and ipm. the green lacewing, chrysoperla carnea (stephens) is a polyphagous predator attacking several pests on various crops. this experiment was conducted under laboratory conditions at 25 ± 2 °c, 60 ± 5% r. h. and a photoperiod of 16l: 8d h. the effects of different prey species were investigated...

background and aims. the purpose of this investigation was to assess the placement and replacement of resin-based composite restorations and related factors in a private practice in greece. materials and methods. the study included 1500 subjects, 720 males and 780 females, aged 18 to 52 years old. the clinical examination involved calculation of the number of teeth with primary caries and faile...

The genetic contribution to the variation in human lifespan is ∼ 25%. Despite the large number of identified disease-susceptibility loci, it is not known which loci influence population mortality. We performed a genome-wide association meta-analysis of 7729 long-lived individuals of European descent (≥ 85 years) and 16 121 younger controls (<65 years) followed by replication in an additional se...