Cardiac amyloidosis presents a picture of hypertrophic cardiomyopathy with heart failure preserved ejection fraction. It is largely underdiagnosed, especially in black Africans, and therefore falls under the category disease classified as idiopathic. Light chain (AL) mainly found Caucasian subjects mutant variant transthyretin (TTRm) negroid subjects. Numerous studies have shown that ATTRm was ...

patients and methods in this cross-sectional study, we evaluated all patients referred to a single rheumatology clinic for bone mineral density measurements from 2009 to 2010. all patients who had bone mineral density measurements taken from the hip, lumbar spine, forearm, and whole body were enrolled in the study. standard bone mineral density measurements were performed using a dual energy x-...

Bone scintigraphy or whole-body bone scan is one of the most common diagnostic procedures in nuclear medicine used in the last 25 years. Pathological conditions, technically poor image resolution and artefacts necessitate that algorithms use sufficient background knowledge of anatomy and spatial relations of bones in order to work satisfactorily. A robust knowledge based methodology for detecti...

Cancer patients with spinal metastases are a diagnostic and treatment challenge for the clinician. This challenge must be addressed through a multidisciplinary, multimodal, and individualized management. The presence of tumor cells in bone metastases results in homeostatic disruption between bone formation and remodeling. Bone destruction is a late event in the formation of lytic bone metastasi...