A bioassay-guided isolation of antifungal compounds from an African land race of ginger, Zingiber officinale Roscoe, led to the identification of [6], [8] and [10]-gingerols and [6]-gingerdiol as the main antifungal principles. The compounds were active against 13 human pathogens at concentrations of <1 mg/mL. The gingerol content of the African land race was at least 3 x higher than that of ty...

Reactive oxygen species [ROS] cause oxidative damage to the tissues and protection from such damages are provided by endogenous and exogenous antioxidants. Plant based antioxidants are preferred due to the multiple mechanisms of actions and of the phytochemicals present in them. 80% alcoholic extract of leaves of Aloe vera, Bacopa monniera, Moringa oleifera and rhizome of Zingiber officinale wa...

abstract background and objective: according to the importance of learning and memory in the human life and also unavoidable neural degeneration due to aging, finding new compounds (drugs) against this process is valuable. however, there are many recommendations for herbal medicine and constituents which encouraged us to examine a candidate plant zingiber officinalis for the mentioned purpose. ...

The study investigates the phytochemistry, Gas-Chromatography–Mass Spectrometry (GC-MS), atomic Absorbtion spectroscopy (AAS) and antidiabetic activities of aqueous ginger (Zingiber officinale) extract in diabetic alloxan-induced Wistar rats. Qualitative phytochemical analysis, GC-MS, AAS properties were determined using standard procedures. Phytochemical analysis shows that contains tannins, f...

Alcoholic extracts of the rhizomes of Alpinia galanga, Andrographis paniculata, bark of Cinnamomum zeylanicum, rind of Citrus decumana, Desmodium triflorum, seeds of Hydnocarpus wightiana, rhizomes of Kaempfaria galanga, Lippia nodiflora, tender leaves of Morinda citrifolia, rhizomes of Pollia serzogonian, Tephrosia purpuria and rhizomes of Zingiber zerumbeth showed good in vitro anthelmintic a...

INTRODUCTION In this study, we used dichloromethane (DCM) and methanol (MeOH) extracts of the Zingiber zerumbet rhizome to evaluate brine shrimp lethality and larvicidal activity on Aedes aegypti and Anopheles nuneztovari mosquitoes. METHODS Bioassays were performed by exposing third-instar larvae of each mosquito species to the DCM or MeOH extracts. RESULTS Probit analysis with DCM and MeO...

Antimicrobial properties of phytochemicals extracted from onion (Allium cepa) and ginger (Zingiber officinale) were evaluated against Escherichia coli and Staphylococcus aureus, two common food borne pathogens. They were tested using minimum inhibitory concentration, minimum bactericidal concentration disc diffusion and agar wells diffusion. Onion showed good antimicrobial properties against S....

The antibacterial and anti-biofilm activity of ethanolic extract from the rhizome of Zingiber officinale were evaluated. In vitro antibacterial activity was investigated by microdilution method. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) have been determined. The values were in the range from 0.0024 to > 20 mg/ml. The most sensitive bacteria were Gram-po...