objective: the spice zingiber officinale or ginger possesses antioxidant activity and neuroprotective effects. the effects of this traditional herbal medicine on 3,4-methylenedioxymethamphetamine (mdma) induced neurotoxicity have not yet been studied. the present study considers the effects of zingiber officinale on mdma-induced spatial memory impairment and apoptosis in the hippocampus of male...

BACKGROUND Trichomoniasis is the most common sexually transmitted protozoan diseases in the worldwide. Metronidazole is the choice drug for trichomoniasis treatment, however, metronidazole resistant Trichomonas vaginalis (T.vaginalis) has been reported. Natural products are the source of most new drugs, and Zingiber officinale (Ginger) is widely used ingredient in the traditional medicine. OB...

Nephrotoxicity is the main complication of gentamicin (GM) treatment. GM induces renal damage by overproduction of reactive oxygen species and inflammation in proximal tubular cells. Phenolic compounds from ginger, called gingerols, have been demonstrated to have antioxidant and anti-inflammatory effects. We investigated if oral treatment with an enriched solution of gingerols (GF) would promot...

BACKGROUND/OBJECTIVE Zingiber officinale Roscoe (ginger) (Zingiberaceae) has been cultivated for thousands of years both as a spice and for medicinal purposes. Ginger rhizomes successive extracts (petroleum ether, chloroform and ethanol) were examined against liver fibrosis induced by carbon tetrachloride in rats. RESULTS The evaluation was done through measuring antioxidant parameters; gluta...

Ginger is one of the most important natural medicinal plant which is used for the various traditional and medicinal purposes in India as well as china, Caribbean, Africa and African countries this natural gift consumed worldwide as a spice and flavouring agent from the ancient time. Ginger has been used for the centuries to support many various digestive imbalances including, indigestion, nause...

Zingiber officinale belonging to Zingiberaceae family is used worldwide as a cooking spice, condiment and herbal remedy. This study was taken up to investigate the anxiolytic activity of alcohol and water extracts of the rhizomes of Zingiber officinale.in mice, by behavioral tests like elevated plus maze (EPM) and open field test (OFT) which will serve as the basis for assessing anxiolytic effe...