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چکیده هدف: توسعۀ ورزش ملی نیازمند همکاری و حمایت ذینفعان درگیر در ورزش ملی است تا بتوان برنامه های توسعۀ ورزش را به وسیلۀ این ذینفعان اجرا کرد، ولی سازمان ها در این مورد با چالشی به نام مشروعیت سازمانی مواجه هستند و این تحقیق با هدف طراحی الگوی تامین منافع ذینفعان وزارت ورزش و جوانان با تاکید بر مشروعیت سازمانی انجام شد. روش شناسی: روش پژوهش توصیفی از نوع همبستگی است که به شکل میدانی انجام گر...
OBJECTIVES To examine the association of living arrangements with functional disability among older persons and explore the mediation of impact factors on the relationship. DESIGN Cross-sectional analysis using data from Healthy Aging study in Zhejiang Province. PARTICIPANTS Analyzed sample was drawn from a representative rural population of older persons in Wuyi County, Zhejiang Province, ...
BACKGROUND Wet cupping therapy is a complementary therapy in pain management. The mechanism of this therapy, however, needs further elucidation. Cells injured by wet cupping therapy seem to stimulate the expression of heat shock protein 70 (HSP70). Its benefit in pain reduction could be mediated by the expression of ß-endorphin. This study aimed at determining the correlation between HSP70 and ...
Patients with Malignant Mesothelioma (MM) develop unidentified auto-antibodies to MM tumour antigens. This study was conducted to identify the targets of MM patient auto-antibodies in order to try to understand more of the anti-tumour response and to determine if these antibodies might be helpful for diagnosis or prognostication. Using MM patient sera in a Western immunoblott screening strategy...
The relationship between the sodium nitroprusside (SNP) test for ketone bodies in urine and concentrations of serum ß-hydroxybutyrate (ß-HB) was studied in 50 Holstein Friesian cows on a commercial dairy farm, including 10 cows in the dry period, and 22, 8 and 10 cows and in week 2, 4 and 8 of lactation, respectively. Urine and blood samples were collected from all cows and were transported to ...
Abstract Objective To investigate the relationship between physical capacity and health-related quality of life (HRQoL) in older patients with symptomatic knee osteoarthritis (KOA). Method A cross-sectional study was carried out, which 67 people (55 women 12 men) diagnosed KOA completed function tests: Timed Up Go (TUG); 30-second Chair Stand Test (30CST); Stair Climb (SCT); 40m Fast-Paced Walk...
The nuclear orphan receptor peroxisome proliferator-activated receptor-gamma (PPAR-γ) is expressed in multiple cell types in addition to adipocytes. Upon its activation by natural ligands such as fatty acids and eicosanoids, or by synthetic agonists such as rosiglitazone, PPAR-γ regulates adipogenesis, glucose uptake and inflammatory responses. Recent studies establish a novel role for PPAR-γ s...
BACKGROUND Although TGF-ß and the transcription factor Egr-1 play an important role in both kidney fibrosis and in response to acute changes of renal medullary osmolarity, their role under sustained hypo- or hyperosmolar conditions has not been elucidated. We investigated the effects of chronic hypertonicity and hypotonicity on the renal medullary TGF-ß and Egr-1 expression. METHODS Male adul...
Colorectal cancer (CRC) is one of the most common and deadly malignancies in the world. Most CRCs are initiated by aberrant activation of the Wnt/ß-catenin signaling pathway. Despite the advances in its early diagnosis, optimized surgical approaches, and chemotherapies, the clinical management of advanced CRC requires effective adjuvant agents. Ginsenoside Rg3 is a single compound isolated from...
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