The IL-2 receptor (IL-2R) α chain (CD25), but not the IL-2R β chain, is induced on dendritic cells (DC) by brief periods of culture. To test if this IL-2Rα is important for DC function, DC were isolated from the spleens of mutant mice with the IL-2Rα gene disrupted and compared with normal DC for ability to stimulate proliferation of allogeneic CD4 and CD8 T cells in culture. The IL-2Rα null DC...

It is a major problem in topological geometry to describe all compact projective planes P with an automorphism group Σ of sufficiently large topological dimension. This is greatly facilitated if the group is known to be a Lie group. Slightly improving a result from the first author’s dissertation, we show for a 16-dimensional plane P that the connected component of Σ is a Lie group if its dimen...

Many employers screen new hires by examining the credit reports of job applicants. The practice has sparked debate, with opponents asserting that it amounts to discrimination and proponents maintaining that it is an important tool for employers to assure the quality of new employees. To date, little evidence exists on the validity of credit status as a screening device. The issue is complicated...

A large body of research documents the importance of early life conditions for the health and human capital formation of children. The detrimental effects of alcohol exposure in utero are well documented, and therefore identifying effective methods for preventing harmful maternal alcohol consumption is of great importance. We exploit the stepwise introduction of alcohol screening and brief inte...