Valienamine (1) i s the unsaturated derivative of carbocyclic analogues of glycosylamines. I ts αand β-anomeric i somers ar e n ot i nterconvertible each o ther, existing as chemically stable forms (Fig. 1). Compound 1 was first isolated from antibiotic v alidamycins a nd f ound t o pos sess a s trong i nhibitory a ctivity a gainst α-glucosidase. It was also shown as one of the components of ps...

The filamentous fungus Hypocrea jecorina produces a number of cellulases and hemicellulases that act in a concerted fashion on biomass and degrade it into monomeric or oligomeric sugars. β-Glucosidases are involved in the last step of the degradation of cellulosic biomass and hydrolyse the β-glycosidic linkage between two adjacent molecules in dimers and oligomers of glucose. In this study, it ...

Commercial cellulase complexes produced by cellulolytic fungi contain enzyme activities that are capable of hydrolyzing non-cellulosic polysaccharides in biomass, primarily hemicellulose and pectins, in addition to cellulose. However, xylanase activities detected in most commercial enzyme preparations have been shown to be insufficient to completely hydrolyze xylan, resulting in high xylooligom...

In this research, food (cheese, yoghurt) and animal (chicken) origin 39 Lactobacillus spp. human (newborn faeces) three Bifidobacterium were used. To designate the β-glycosidase enzyme specific activities of cultures, p-nitrophenyl-β-D glikopiranozit (p-NPG) was used as a substrate. The best between Lactobacilli cultures observed at rhamnosus BAZ78 (4.500 U/mg), L. SMP6-5 (2.670 casei LB65 (3.0...

BACKGROUND In general, biofuel production involves biomass pretreatment and enzymatic saccharification, followed by the subsequent sugar conversion to biofuel via fermentation. The crucial step in the production of biofuel from biomass is the enzymatic saccharification. Many of the commercial cellulase enzyme cocktails, such as Spezyme(®) CP (Genencor), Acellerase™ 1000 (Genencor), and Cellucla...

A total of 10 cellulase-producing bacteria were isolated from soil samples irrigated with paper and pulp mill effluents. The sequencing of 16S rRNA gene revealed that all isolates belonged to different species of genus Bacillus. Among the different isolates, B. subtilis IARI-SP-1 exhibited a high degree of β-1,4-endoglucanase (2.5 IU/ml), β-1,4-exoglucanase (0.8 IU/ml), and β-glucosidase (0.084...

BACKGROUND Recently, the increased demand of energy has strongly stimulated the research on the conversion of lignocellulosic biomass into reducing sugars for the subsequent production, and β-glucosidases have been the focus because of their important roles in a variety fundamental biological processes and the synthesis of useful β-glucosides. Although the β-glucosidases of different sources ha...

www.experimentjournal.com 1254 Synthesis, biological activity and docking studies of N,N'-(3S,4S)bis(3,4-disubstituted pyrrolidine)-1-sulfonamide derivatives as β-gluscosidase inhibitors Abstract Starting with L-tartaric acid the chiral 3,4-disubstituted pyrrolidine analogue sulfonamide derivatives were prepared. These compounds were examined for anti-bacterial and anti-fungal activity. Further...