We compute the large-body and the small-particle Gamma-limit of a family of energies for nematic elastomers. We work under the assumption of small deformations (linearized kinematics) and consider both compressible and incompressible materials. In the large-body asymptotics, even if we describe the local orientation of the liquid crystal molecules according to the model of perfect order (Frank ...

Interferon gamma (IFN-γ) is one of the key cytokines in defining T helper 1 lymphocyte immuneresponses. In this study, the bovine IFN-γ gene was cloned from spleen tissue RNA using the reversetranscription-polymerase chain reaction (RT-PCR). IFN-γ cDNA was sub-cloned and expressed inmammalian expression plasmid (pcDNA3.1(+)) under the control of the human cytomegalovirus (CMV)promoter. The pred...

Umbelliprenin is a sesquiterpene coumarin with vitro anti-carcinogenic activities. The aim of this study was to investigate the antitumor effects of umbelliprenin in animal models of colorectal cancer. The cytotoxic effects of umbelliprenin were explored on CT26 and L929by MTT assay. In this study, colorectal tumors developed in mice by intradermal injection of CT26 cell line. Tumor size, serum...

Umbelliprenin is a sesquiterpene coumarin with vitro anti-carcinogenic activities. The aim of this study was to investigate the antitumor effects of umbelliprenin in animal models of colorectal cancer. The cytotoxic effects of umbelliprenin were explored on CT26 and L929by MTT assay. In this study, colorectal tumors developed in mice by intradermal injection of CT26 cell line. Tumor size, serum...

Background and purpose: Recent research suggests that obese people are up to 80 times more likely to develop type 2 diabetes than those with a normal BMI. Besides, obesity, inadequate physical activity, and unhealthy diets are the main causes of this metabolic disease. The purpose of this study was to investigate the effect of six weeks of high-intensity interval training on muscle expression o...

background: the effect of low dose radiation on immune system is shown. ionizing radiation can affect cytokine production and polarization of t helper cells. objective: the current study focused on ionizing radiation in ukrainian children residing in a contaminated area with clinical irritable bowel syndrome. method: our study included 75 rural children population aged 4-18 yrs, who lived in a ...

OBJECTIVE To determine if orally dosed γ-glutamylcysteine (γ-GC) can increase cellular glutathione (GSH) levels above homeostasis. Many chronic and age-related disorders are associated with down-regulation, or impairment, of glutamate cysteine ligase (GCL). This suggests that γ-GC supply may become limiting for the maintenance of cellular GSH at the normal levels required to effectively protect...

Mucosal immune activation and altered serotonin metabolism participate in the pathophysiology of irritable bowel syndrome (IBS). However, the reciprocal interplay between these two systems remains unknown. We evaluated the expression and release of interferon (IFN)-γ from the colonic mucosa of patients with IBS and its impact on serotonin reuptake transporter (SERT) gene expression in Caco-2 ce...

Increased γ/δ-positive T-cells in blood and bronchoalveolar lavage of patients with sarcoidosis and hypersensitivity pneumonitis. M. Raulf, V. Liebers, C. Steppert, X. Baur. ERS Journals Ltd 1994. ABSTRACT: A small population of T-cells does not express the conventional Tcell receptor (TCR), characterized by the α and β polypeptide chains (α/β TCR) but two polypeptides termed γ and δ (γ/δTCR)....