Human tissue-specific genome-scale metabolic models (GEMs) provide comprehensive understanding of human metabolism, which is of great value to the biomedical research community. To make this kind of data easily accessible to the public, we have designed and deployed the human metabolic atlas (HMA) website (http://www.metabolicatlas.org). This online resource provides comprehensive information a...

Hot mixed asphalt (HMA) is a mixture of particles (coarse and fine aggregates) interstitial fluid (asphalt binder) designed to compact harden for long-lasting roads. In this study, we implement two-scale approach capture the compaction behaviour hot mixtures using both granular-slurry rheology (GSR) at smaller scale discrete element method (DEM) simulation compactor. We show that modelling effo...

Abstract High Mountain Asia (HMA) glaciers are critical water reserves for montane regions, which readily influenced by climate change. The glacier mass balance during 2000–2021 over HMA was estimated comparing the elevations from ICESat-2 and NASADEM. Radar penetration depth could be one of intrinsic error sources in estimating using Therefore, we doubled elevation differences between X-band S...

Several vasoconstrictor agents can regulate the phosphorylation status of the Na(+)-K(+) ATPase (NKA). We have recently demonstrated that mammalian tissues contain an endogenous bufadienolide, digitalis-like alpha(1)-NKA-selective ligand, marinobufagenin (MBG). Protein kinase C induces phosphorylation of the alpha(1)-NKA isoform, the major isoform in vascular smooth muscle, kidney, and heart ce...

Studi ini membandingkan dampak lingkungan dari produksi campuran aspal hangat (Warm Mix Asphalt – WMA) dimodifikasi polimer EVA dengan dosis 5% berat bitumen melalui metode pencampuran kering (dry mixing) panas (Hot HMA) standar pada skala laboratorium menggunakan Life Cycle Assessment (LCA,) lingkup akuisisi bahan baku hingga di Universitas Pelita Harapan. Kajian menggabungkan database CML-IA ...