Idiopathic pulmonary fibrosis has a poor prognosis and few efficacious treatments. The immunosuppressant cyclosporin A has been shown to inhibit tumour growth factor (TGF)-beta-induced collagen deposition in vitro, and is widely used in Japan as a potent antifibrotic agent. Tacrolimus (FK506) is another attractive immunosuppressant, which may be useful in the treatment of pulmonary fibrosis. Th...

Polypeptides emerging from the ribosome are assisted by a pool of molecular chaperones and targeting factors, which enable them to efficiently partition as cytoplasmic, integral membrane, or exported proteins. In Escherichia coli, the chaperones SecB, Trigger Factor (TF), and DnaK are key players in this process. Here, we report that, as with dnaK or dnaJ mutants, a secB null strain exhibits a ...

The prediction of the weld bead geometry parameters is an important aspect welding processes due to it related strength welded joint. This research focuses on using statistical design techniques and a deep learning neural network predict shape shielded metal arc (SMAW), inert gas (MIG), tungsten (TIG) processes. With techniques, experiments were carried out obtain data for generating regression...

Fin-shaped Field-Effect Transistors} (FinFETs) with Three Independent Gates (TIG) have been recently demonstrated capable of an ultra-steep-slope operation down to 3.4mV/dec. In this paper, we explore their opportunities in the domain of analog design and terahertz detectors. We see that they could result in analog circuits with 25× power efficiency improvement and in THz detectors with 2 order...

We describe the TIG formalism and its advantages over CFGs and TAGs. We then give an algorithm for training PLTIGs following Hwa (2001). We train on a partially supervised corpus by repeated parsing with a lexicalized normal form. The training algorithm is EM-style, and the parsing algorithm is a generalization of CKY. Finally, we look toward the possibility of extending this method into a sync...