نتایج جستجو برای: آگهی خدمات عمومی psa

تعداد نتایج: 71573  

Journal: :Clinical chemistry 2002
Takahiro Isono Tsutomu Tanaka Susumu Kageyama Tatsuhiro Yoshiki

BACKGROUND Heterogeneity among the various molecular forms of prostate-specific antigen (PSA) has not been well characterized, despite the critical importance of PSA in the detection of prostate cancer. The purpose of this study was to examine PSA heterogeneity in cancerous and noncancerous materials by extensive and systematic protein analysis. METHODS A catalog of molecular forms of PSA was...

Journal: :Journal of molecular recognition : JMR 2006
Catherine Ferrieu-Weisbuch Sandrine Michel Emilie Collomb-Clerc Catherine Pothion Gilbert Deléage Colette Jolivet-Reynaud

Prostate-specific antigen (PSA) is an important marker for the diagnosis and management of prostate cancer. Free PSA has been shown to be more extensively cleaved in sera from benign prostatic hyperplasia patients than in sera from prostate cancer patients. Moreover, the presence of enzymatically activatable PSA was characterized previously in sera from patients with prostate cancer by the use ...

Journal: :Urology 2002
Carsten Stephan Klaus Jung Eleftherios P Diamandis Harry G Rittenhouse Michael Lein Stefan A Loening

P antigen (PSA) is a serine protease produced by the prostate gland at very high concentrations. PSA is secreted into the seminal plasma in high concentrations (0.5 to 5 g/L), where it plays a role in semen liquefaction. The retrograde release of PSA into the bloodstream is a rare event in young, healthy men. It occurs with a frequency of less than one PSA molecule per million secreted PSA mole...

2013
Harold S. Haller J. Stephen Jones Ayman Moussa Ahmed El-Shafei Tanujit Dey

PSA measurements are used to assess the risk for prostate cancer. PSA range and PSA kinetics such as PSA velocity have been correlated with increased cancer detection and assist the clinician in deciding when prostate biopsy should be performed. Our aim is to evaluate the use of a novel, maximum likelihood estimation prostate specific antigen (MLE-PSA) model for predicting the probability of pr...

ژورنال: فصلنامه رأی 2018

خدمات عمومی به عنوان مهم ترین مبنای حقوق اداری تابع اصولی است که از آن به عنوان اصول حاکم بر خدمات عمومی یاد می شود .این اصول که نخستین بار در نظام حقوق اداری فرانسه شناسایی شدند و سپس به سایر نظام های حقوق اداری راه یافتند عبارتند از اصل برابری ، استمرار، انطباق و تقدم منفعت عمومی بر خصوصی.در این مقاله به بررسی اصل استمرار خدمات عمومی به عنوان یکی از اصول مهم مرتبط با خدمات عمومی می پردازیم.اص...

Journal: :Clinical chemistry 2005
Yvonne Baumgart Andreas Otto Angelika Schäfer Elke Usbeck Christiane Cott Astrid Schott Maria Tornack Anett Wenzel Andualem Mossie Gerd Birkenmeier

BACKGROUND Different molecular forms of prostate-specific antigen (PSA) have been used to differentiate between benign prostatic hyperplasia and prostate cancer. Detecting PSA bound to endogenous inhibitors such as alpha(1)-antichymotrypsin (ACT) and alpha(2)-macroglobulin (alpha(2)M) is often difficult because of epitope masking or sensitivity problems. Here we report the characterization of f...

Journal: :Journal of clinical laboratory analysis 1999
G H Borchert H Yu G Tomlinson M Giai R Roagna R Ponzone L Sgro E P Diamandis

We have analyzed matched serum and breast cyst fluid samples for total PSA from 148 patients with fibrocystic breast disease. We have also determined the molecular forms of PSA (free PSA and PSA bound to alpha1-antichymotrypsin) in 78 breast cyst fluid samples. We found that total PSA can be detected in all cyst fluids and in about 75% of female sera. The median total PSA concentration in breas...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002
Fan J Meng Ailin Shan Long Jin Charles Y F Young

Although a splicing variant of prostate specific antigen (PSA-v) mRNA has been described previously, whether its protein (PSA-v or PSA-related protein 1, i.e., PSA-RP1) is actually expressed in human prostate cells remains elusive. We report that PSA-v protein is expressed in prostatic epithelia of both cancerous and benign tissues. Also, secreted PSA-v can be detected in the medium of a prosta...

ژورنال: :مجله پزشکی ارومیه 0
رضا نکوئیان reza nekouian iran university of medical sciencesدانشگاه علوم پزشکی ایران بهاره سادات رسولی bahareh sadat rasouli iran university of medical sciencesدانشگاه علوم پزشکی ایران

پیش زمینه و هدف: نانوذرات توجه بسیاری در حوزه های مختلف شامل زیست شناسی، پزشکی و به تازگی پزشکی قانونی به دلیل ویژگی های اختصاصی آن جلب کرده است. بیشتر شواهدی که در یک بخش زیستی پزشکی قانونی مواجه می شویم بیشتر شامل تجاوز جنسی می باشد و توانایی شناسایی دقیق منی (باوجود اسپرم یا بدون وجود اسپرم) در چنین مواردی یک جزء ضروری در آزمایش های سرولوژی است. psa یک نشانگر جهت شناسایی منی است و غلظت آن در...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2002
Hiroshi Terasawa Kwong-Yok Tsang James Gulley Philip Arlen Jeffrey Schlom

One potential target of vaccine therapy for human prostate cancer is the prostate-specific antigen (PSA). One strategy to enhance the immunogenicity of a self-antigen such as PSA is to develop agonist epitopes that are potentially more immunogenic. The studies described here report the design and analysis of an agonist epitope designated PSA-3A ("A" for agonist) of the PSA-3 CTL epitope. Studie...

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