The purpose of this study is to evaluate the use of arabinoxylan as potential suspending agent, an effective alternative to commercially used excipients for the preparation of pharmaceutical suspensions. Alkali extraction was done to separate arabinoxylan from ispaghula (Plantago ovata) seed husk by alkali extraction its physicochemical characterization was done and the suspending properties of...

The present study deals with isolation of different polysaccharides from Plantago Ovata husk and their use in designing the controlled release Gastro-Retentive (GR) floats of piroxicam (PRC). Gastroretentive floats are actually drug release (DR) moieties of low density used to retain the drug in stomach for maximum time to increase its bioavailability. The polysaccharides extracted from P. Ovat...

Objective: Development of resistance against many of the commonly used antibiotics is an impetus for further efforts to search for new antimicrobial agents. The aim of the study was determined as antibacterial activity of silver nanoparticles produced by Plantago ovata seed extract against Pseudomonas aeruginosa. Methods: All 30 strains of P. aeruginosa wereisolated f...

BACKGROUND & AIMS Dietary fiber has been proven to be beneficial in maintaining remission in human ulcerative colitis, an effect related with an increased luminal production of short-chain fatty acids (SCFA). The aim of the present study was to further investigate the mechanisms involved in the intestinal anti-inflammatory effects of dietary fiber in an experimental model of rat colitis. METH...

Several studies have suggested that the partially fermentable fibre Plantago ovata husk (PO) may have a protective effect on colorectal cancer (CRC). We studied the potentially pro-apoptotic effect of PO and the implicated mechanisms in CRC cells with different molecular phenotypes (Caco-2, HCT116, LoVo, HT-29, SW480) after PO anaerobic fermentation with colonic bacteria as it occurs in the hum...