A 15-Country collaborative cohort study was conducted to provide direct estimates of cancer risk following protracted low doses of ionizing radiation. Analyses included 407,391 nuclear industry workers monitored individually for external radiation and 5.2 million person-years of follow-up. A significant association was seen between radiation dose and all-cause mortality [excess relative risk (E...

Purpose. Most MRI centers currently use prospective ECG triggering and fast gradient-echo sequences for image acquisition. Retrospectively gated sequences allow the coverage of the entire cardiac cycle. There is concern about whether ventricular volumes and ejection fraction (EF) differ according to the gating method used for image acquisition. We sought to evaluate the impact of the gating met...

PURPOSE Most magnetic resonance imaging (MRI) centers currently use prospective electrocardiographic (ECG) triggering for image acquisition. Retrospectively gated sequences allow the coverage of the entire cardiac cycle. It has been recently shown that ventricular volumes and ejection fraction (EF) differ according to the gating method used for image acquisition. The authors sought to evaluate ...

BACKGROUND In the assessment of hypovolemia the value of functional hemodynamic monitoring during spontaneous breathing is debated. The aim of our study was to investigate in spontaneously breathing subjects the changes in hemodynamic parameters during graded central hypovolemia and to test whether slow patterned breathing improved the discriminative value of stroke volume (SV), pulse pressure ...

PURPOSE Most MRI centers currently use prospective ECG triggering and fast gradient-echo sequences for image acquisition. Retrospectively gated sequences allow the coverage of the entire cardiac cycle. There is concern about whether ventricular volumes and ejection fraction (EF) differ according to the gating method used for image acquisition. We sought to evaluate the impact of the gating meth...

Simvastatin (SV) is a semisynthetic derivative of lovastatin (LV), which biosynthetically produced from the fungus Aspergillus terreus and has high log p value (log = 4.39)and thus hepatic extraction efficacy in controlling cholesterol synthesis. The current study was undertaken to investigate metabolic profile SV using various mass spectrometry (MS) platforms. Metabolic profiling studied vitro...

Effects of hemodialysis on extracellular fluid volume distribution, left ventricular volumes, and cardiac output were determined in patients with end-stage renal disease (n = 19). Distribution of extracellular fluid loss from hemodialysis differed widely among patients, so that weight change correlated weakly with contraction of total blood volume (index of determination 29%, p less than 0.05)....

Abstract Background There are few non-invasive monitoring methods that can reliably predict fluid responsiveness (FR) in children. Here, we interrogate the value of doppler ultrasound evaluation passive leg raising (PLR)-induced changes stroke volume (SV) and cardiac output (CO) as a predictor FR children with mechanical ventilation after congenital surgery. Methods A total 40 following surgery...

Among different discretization approaches, Finite Difference Method (FDM) is widely used for acoustic and elastic full-wave form modeling. An inevitable deficit of the technique, however, is its sever requirement to computational resources. A promising solution is parallelization, where the problem is broken into several segments, and the calculations are distributed over different processors. ...

Objective: To assess whether flow-mediated dilatation (FMD) affected cardiovascular (CV) parameters after consuming fructose or sucralose. Data source: Finometer. Design of study: Randomized, cross-over, single-blind design. Setting: School of biomedical sciences, University of Nottingham, UK. Period: July, 2009. Materials and methods: Ten healthy, white European males were studied twice. A Fin...