Advances in direct radiocarbon dating of Neanderthal and anatomically modern human (AMH) fossils and the development of archaeostratigraphic chronologies now allow refined regional models for Neanderthal-AMH coexistence. In addition, they allow us to explore the issue of late Neanderthal survival in regions of Western Eurasia located within early routes of AMH expansion such as the Caucasus. He...

Status of This Memo This document specifies an Internet standards track protocol for the Internet community, and requests discussion and suggestions for improvements. Please refer to the current edition of the "Internet Official Protocol Standards" (STD 1) for the standardization state and status of this protocol. Distribution of this memo is unlimited. Abstract The Link Management Protocol (LM...

Locational marginal pricing (LMP) is a widely employed method for pricing electricity in the wholesale electricity market. Although it is well known that the LMP mechanism is vulnerable to market manipulation, there is little literature providing a systematic analysis of this phenomenon. In the first part of this paper, we investigate the economic dispatch outcomes of the LMP mechanism with str...

This paper concerns labelled Markov processes (LMPs), probabilistic models over uncountable state spaces originally introduced by Prakash Panangaden and colleagues. Motivated by the practical application of the LMP framework, we study its formal semantics and the relationship to similar models formulated in control theory. We consider notions of (exact and approximate) probabilistic bisimulatio...

This paper is concerned with path planning of highly redundant manipulators, which are particularly well suited for flexible manufacturing. We envision that highly redundant manipulators will be composed of a set of standard modules. In order to find the optimal configuration of modules, one has to perform a discrete search on possible assemblies of modules combined with a continuous search of ...

SCOPE We aimed to investigate the effects of three different soluble pectins on the digestion of other consumed carbohydrates, and the consequent alterations of microbiota composition and SCFA levels in the intestine of pigs. METHODS AND RESULTS Piglets were fed a low-methyl esterified pectin enriched diet (LMP), a high-methyl esterified pectin enriched diet (HMP), a hydrothermal treated soyb...

Although glomerular and vascular damage have been considered the main characteristics of diabetic kidney disease (DKD), accumulating data now indicate that tubular atrophy also plays a major role. Cathepsin D (CatD) is the major aspartate protease within lysosomes. The current study demonstrated that CatD expression was altered in the renal tubular epithelium in patients with diabetes mellitus ...

Recent studies of school-age children and adolescents have used social network analyses to characterize selection and socialization aspects of peer groups. Fewer network studies have been reported for preschool classrooms and many of those have focused on structural descriptions of peer networks, and/or, on selection processes rather than on social functions of subgroup membership. In this stud...

Myotropic neuropeptides have been isolated from vertebrates and invertebrates. Recently, a myoinhibitory peptide from the protist Leishmaniamajor was isolated, and its function in the sand fly vector was described. Similar lysates of cultured L. major were tested for their ability to inhibit contractions in mammalian cell and tissue preparations. L. major proteins (LMP) (34 microg/ml) completel...

Latent Epstein-Barr virus (EBV) infection activates B-lymphocyte proliferation through mechanisms which are partially known. One approach to further delineate these mechanisms is to identify cellular genes whose expression is augmented in cells latently infected with EBV. Since EBV-negative Burkitt's lymphoma cells can be grown in continuous culture and EBV can establish growth-altering latent ...