The finding that N-glycoloylneuraminic acid (Neu5Gc) in pig submandibular gland is synthesized by hydroxylation of the sugar nucleotide CMP-Neu5Ac [Shaw & Schauer (1988) Biol. Chem. Hoppe-Seyler 369, 477-486] prompted us to investigate further the biosynthesis of this sialic acid in mouse liver. Free [14C]Neu5Ac, CMP-[14C]Neu5Ac and [14C]Neu5Ac glycosidically bound by Gal alpha 2-3- and Gal alp...

Mistletoes are used medicinally in order to treat various human illnesses. Few studies have reported on the phenolic content and antioxidant properties of Chinese mistletoes (CMs). In this work, the total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activities of soluble and insoluble-bound phenolic extracts from CMs hosted by Camellia assamica (Mast.) Chang (CMC) and ...

In this paper, we introduce a new combinatorial optimization problem entitled the color mix (CMP), which is more general case of grey pattern quadratic assignment (GP-QAP). Also, propose an original hybrid genetic-iterated tabu search algorithm for heuristically solving CMP. addition, present both analytical solutions and graphical visualizations obtained solutions, clearly demonstrate excellen...

Angiopoietin-1 (Ang1), a potential growth factor for therapeutic angiogenesis and vascular stabilization, is known to specifically cluster and activate Tie2 in high oligomeric forms, which is a unique and essential process in this ligand-receptor interaction. However, highly oligomeric native Ang1 and Ang1 variants are difficult to produce, purify, and store in a stable and active form. To over...

This paper reports a novel fabrication process to develop planarized isolated islands of benzocyclobutene (BCB) polymer embedded in a silicon substrate. Embedded BCB in silicon (EBiS) can be used as an alternative to silicon dioxide in fabrication of electrostatic micromotors, microgenerators, and other microelectromechanical devices. EBiS takes advantage of the low dielectric constant and ther...

Simultaneous multithreading (SMT) and chip multiprocessing (CMP) both allow a chip to achieve greater throughput, but their thermal properties are still poorly understood. This paper uses Turandot, PowerTimer, and HotSpot to evaluate the thermal efficiency for a Power4/Power5-like core. Our results show that although SMT and CMP exhibit similar peak operating temperatures, the mechanism by whic...

Human UMP/CMP kinase (EC 2.7.4.14) is responsible for phosphorylation of CMP, UMP, and dCMP and also plays an important role in the activation of pyrimidine analogs, some of which are clinically useful anticancer or antiviral drugs. Previous kinetic data using recombinant or highly purified human UMP/CMP kinase showed that dCMP, as well as pyrimidine analog monophosphates, were much poorer subs...

INTRODUCTION Interactions of the ceria particles with polyurethane surfaces are of great interest for polishing processes used in modern semiconductor industry. Specifically, ceria abrasive nanoparticles and polyurethane polishing pads are now broadly used in the process called Chemical-Mechanical Planarization/Polishing (CMP) [1,2,3]. To optimize the process of CMP, various chemicals, abrasive...